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  1. Griseofulvin, Tubulin inhibitor
    CAS: 126-07-8 Numéro CE: 204-767-4 Formule: C17H17ClO6 Poids moléculaire: 352.77
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G101269
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    Nom IUPAC
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    Synonymes
    CCRIS 320 | Grifulin | (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-...
  2. MK-1775, Serine/threonine-protein kinase WEE1 inhibitor
    CAS: 955365-80-7 Numéro CE: 680-342-0 Formule: C27H32N8O2 Poids moléculaire: 500.61
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: M127160
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    Nom IUPAC
    1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
    SMILES
    CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
    InChIKey
    BKWJAKQVGHWELA-UHFFFAOYSA-N
    InChI
    1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-show more
    Synonymes
    MK-1775(AZD-1775,Adavosertib) | 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenyla...
  3. Griseofulvin
    CAS: 126-07-8 Numéro CE: 204-767-4 Formule: C17H17ClO6 Poids moléculaire: 352.77
    Solid ≥97%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G101270
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    Nom IUPAC
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    Synonymes
    Grisovin | Curling factor | Fulcin | Likuden | Grizeofulvin | Griseofulvina | Grifulvin | Grysio | Delmofulvina | Gri...
  4. PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
    CAS: 185039-89-8 PubChem CID: 5311382 Formule: C26H27Cl2N5O2 Poids moléculaire: 512.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P276244
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    Nom IUPAC
    6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one
    SMILES
    CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
    InChIKey
    IFPPYSWJNWHOLQ-UHFFFAOYSA-N
    InChI
    1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more
    Synonymes
    AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
  5. Bosutinib Isomer 1, Free Base
    CAS: 1391063-17-4 PubChem CID: 5328940 Formule: C26H29Cl2N5O3 Poids moléculaire: 530.45
    ◐ .Sur commande · 8–12 semaines Article #: B330520
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    Synonymes
    Bosutinib,SKI-606 | BSPBio_001023 | NCGC00241107-03 | NSC799367 | NSC-799367 | 4-(2,4-Dichloro-5-methoxy-phenylamino)...
  6. Griseofulvin, Tubulin inhibitor
    CAS: 126-07-8 Numéro CE: 204-767-4 Formule: C17H17ClO6 Poids moléculaire: 352.77
    Liquid 10mM in DMSO
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G421095
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    Identificateurs techniques
    Nom IUPAC
    (2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione
    SMILES
    CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
    InChIKey
    DDUHZTYCFQRHIY-RBHXEPJQSA-N
    InChI
    1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
    Synonymes
    griseofulvin|126-07-8|Amudane|(+)-Griseofulvin|Griseofulvinum|Grisactin|Grifulvin|Grisefuline|Griseofulvina|Grisofulv...
  7. PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
    CAS: 185039-89-8 PubChem CID: 5311382 Formule: C26H27Cl2N5O2 Poids moléculaire: 512.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P422267
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    Identificateurs techniques
    Nom IUPAC
    6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one
    SMILES
    CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl
    InChIKey
    IFPPYSWJNWHOLQ-UHFFFAOYSA-N
    InChI
    1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more
    Synonymes
    AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
  8. Wee1 inhibitor
    CAS: 622855-37-2 PubChem CID: 10384072 Formule: C20H11ClN2O3 Poids moléculaire: 362.77
    ◐ .Sur commande · 8–12 semaines Article #: W342954
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    Nom IUPAC
    4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
    SMILES
    C1=CC=C(C(=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O)Cl
    InChIKey
    DPEXRCOBPACFOO-UHFFFAOYSA-N
    InChI
    1S/C20H11ClN2O3/c21-13-4-2-1-3-10(13)11-8-15-16(18-17(11)19(25)23-20(18)26)12-7-9(24)5-6-14(12)22-15/h1-8,22,24H,(H,23,25,26)
    Synonymes
    BDBM50192371 | Wee1 Inhibitor I | Wee1-Inhibitor-I | MS-25768 | HY-108343 | Wee1 Inhibitor-I | SCHEMBL5828030 | Wee1 ...
  9. Azenosertib (Zn-C3), Inhibitor of WEE1 G2 checkpoint kinase
    CAS: 2376146-48-2 Numéro CE: 189-014-7 PubChem CID: 139467635 Formule: C29H34N8O2 Poids moléculaire: 526.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A607901
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    Identificateurs techniques
    Nom IUPAC
    1-[(7R)-7-ethyl-7-hydroxy-5,6-dihydrocyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
    SMILES
    O=c1n(CC=C)n(c2ccc3CC[C@@](CC)(O)c3n2)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc12
    InChIKey
    OXTSYWDBUVRXFF-GDLZYMKVSA-N
    InChI
    1S/C29H34N8O2/c1-4-14-36-27(38)23-19-30-28(31-21-7-9-22(10-8-21)35-17-15-34(3)16-18-35)33-26(23)37(36)24-11-6-20-12-13-29(39,5-2)25(20)32-24/h4,6-11,1show more
    Synonymes
    compound 16 [PMID: 34423975] | azenosertib | Azenosertib [INN] | EX-A6113 | 9J13XU96Z1 | (R)-2-allyl-1-(7-ethyl-7-hyd...
  10. WEE1-IN-5
    CAS: 2243882-74-6 Formule: C26H28Cl2N6O Poids moléculaire: 511.45
    ◐ .Sur commande · 8–12 semaines Article #: W648831
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    SMILES
    O=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
  11. WEE1-IN-3
    CAS: 2272976-28-8 PubChem CID: 137471996 Formule: C28H31N7O2 Poids moléculaire: 497.59
    ◐ .Sur commande · 8–12 semaines Article #: W648627
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    Identificateurs techniques
    Nom IUPAC
    1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[(2-methylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidishow more
    SMILES
    CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC5=C(C=C4)C6(CC6)CN(C5)C)O
    InChIKey
    JSZFIXAMFNNRKS-UHFFFAOYSA-N
    InChI
    1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37Hshow more
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Foire aux questions

How is the Wee1 listing put together?
It draws on reported Wee1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a Wee1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Wee1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Wee1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Wee1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Wee1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Wee1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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