NVP-BVU972 - ≥98% , CAS No.1185763-69-2

CAS: 1185763-69-2 Cat. No.: N128061 Molecular Weight: 340.38
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
NCGC00346689-02 | (.+/-.)-2-Ethyloxirane | Allylglycide ether | BDBM50146169 | MLS006010964 | AS-56284 | C71592 | RNCNPRCUHHDYPC-UHFFFAOYSA-N | 3qti | Alyl chloride oxide | NCGC00346689-01 | BCP03600 | 1185763-69-2 | 6-{[6-(1-Methyl-1h-Pyrazol-4-Yl)imidaz
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
N128061-1mg
3
$43.90
5mg
N128061-5mg
7
$152.90
25mg
N128061-25mg
5
$490.90
50mg
N128061-50mg
4
$895.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.
A selective and potent Met inhibitor (IC50 = 14 nM)

Specifications

Synonyms
NCGC00346689-02 | (.+/-.)-2-Ethyloxirane | Allylglycide ether | BDBM50146169 | MLS006010964 | AS-56284 | C71592 | RNCNPRCUHHDYPC-UHFFFAOYSA-N | 3qti | Alyl chloride oxide | NCGC00346689-01 | BCP03600 | 1185763-69-2 | 6-{[6-(1-Methyl-1h-Pyrazol-4-Yl)imidaz
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
NVP-BVU972 is a selective and potent Met inhibitor (IC50 = 14 nM). Antitumor agents.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥98%
Names and Identifiers
Pubchem Sid504770312
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504770312
Canonical SmilesCN1C=C(C=N1)C2=NN3C(=NC=C3CC4=CC5=C(C=C4)N=CC=C5)C=C2
IUPAC Name6-[[6-(1-methylpyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]quinoline
InChIKeyRNCNPRCUHHDYPC-UHFFFAOYSA-N
INCHI1S/C20H16N6/c1-25-13-16(11-23-25)19-6-7-20-22-12-17(26(20)24-19)10-14-4-5-18-15(9-14)3-2-8-21-18/h2-9,11-13H,10H2,1H3
Isomeric SMILES CN1C=C(C=N1)C2=NN3C(=NC=C3CC4=CC5=C(C=C4)N=CC=C5)C=C2
Molecular Weight 340.38
Reaxy-Rn 19770146
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19770146&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassQuinolines and derivatives
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentQuinolines and derivatives
Alternative Parents Pyridines and derivatives  Pyridazines and derivatives  N-substituted imidazoles  Benzenoids  Pyrazoles  Heteroaromatic compounds  Azacyclic compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinoline - Benzenoid - Pyridine - Pyridazine - N-substituted imidazole - Heteroaromatic compound - Pyrazole - Imidazole - Azole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MET Tclin Hepatocyte growth factor receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MET Tclin Hepatocyte growth factor receptor (10718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AOX1 Tchem Aldehyde oxidase (429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
G2310584Certificate of AnalysisApr 08, 2025 N128061
G2310585Certificate of AnalysisApr 08, 2025 N128061
G2310587Certificate of AnalysisApr 08, 2025 N128061
G2310588Certificate of AnalysisApr 08, 2025 N128061
G2310590Certificate of AnalysisApr 08, 2025 N128061
G2310592Certificate of AnalysisApr 08, 2025 N128061
G2310593Certificate of AnalysisApr 08, 2025 N128061
G2310596Certificate of AnalysisApr 08, 2025 N128061
Chemical and Physical Properties
SolubilityDMSO 68 mg/mL Water <1 mg/mL Ethanol 68 mg/mL
Molecular Weight340.400 g/mol
XLogP32.500
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass340.144 Da
Monoisotopic Mass340.144 Da
Topological Polar Surface Area60.900 Ų
Heavy Atom Count26
Formal Charge0
Complexity487.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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