Pazufloxacin Mesylate - ≥98%(HPLC) , CAS No.163680-77-1

CAS: 163680-77-1 Cat. No.: P133027 Molecular Weight: 414.4 EC Number: 634-946-6 PubChem CID: 6918232

GRADE & PURITY ≥98%(HPLC)

Synonyms

T-3762 | 3-Dimethylamino-1-propene | D05382 | PazufloxacinMesylate | NSC 759831 | PAZUFLOXACIN METHANESULFONATE [MI] | s3621 | Pasil (TN) | 2XI226J1HS | UNII-2XI226J1HS | NSC-5251 | AKOS015895384 | Pazufloxacin mesylate | (-)-(3S)-10-(1-AMINOCYCLOPROPYL)-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

application：

Pazufloxacin Mesylate (T-3762, Pazucross), also known as Pazucross and T-3762, is a quinolone antibacterial agent used for the intravenous therapy of several infections.

Specifications

Synonyms

T-3762 | 3-Dimethylamino-1-propene | D05382 | PazufloxacinMesylate | NSC 759831 | PAZUFLOXACIN METHANESULFONATE [MI] | s3621 | Pasil (TN) | 2XI226J1HS | UNII-2XI226J1HS | NSC-5251 | AKOS015895384 | Pazufloxacin mesylate | (-)-(3S)-10-(1-AMINOCYCLOPROPYL)-

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Potent and broad spectrum fluoroquinolone antibiotic agent (MIC 90 values are 4 and 9 μM for Staphylococcus aureus and epidermidis respectively). Inhibits topoisomerase IV and DNA gyrase.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%(HPLC)

Names and Identifiers

• Pubchem Sid: 504764355
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764355
• Canonical Smiles: CC1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O
• IUPAC Name: (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;methanesulfonic acid
• InChIKey: UDHGFPATQWQARM-FJXQXJEOSA-N
• INCHI: 1S/C16H15FN2O4.CH4O3S/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22;1-5(2,3)4/h4-5,7H,2-3,6,18H2,1H3,(H,21,22);1H3,(H,2,3,4)/t7-;/m0./s1
• Isomeric SMILES: C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2C4(CC4)N)F)C(=O)O.CS(=O)(=O)O
• PubChem CID: 6918232
• Molecular Weight: 414.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Quinolines and derivatives
      • Subclass Quinoline carboxylic acids

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Quinolines and derivatives
• Subclass: Quinoline carboxylic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoline carboxylic acids
• Alternative Parents: Fluoroquinolones Haloquinolines Hydroquinolones Hydroquinolines Benzoxazines Pyridinecarboxylic acids Alkyl aryl ethers Aralkylamines Benzenoids Aryl fluorides Sulfonyls Organosulfonic acids Alkanesulfonic acids Methanesulfonates Heteroaromatic compounds Vinylogous amides Amino acids Azacyclic compounds Oxacyclic compounds Carboxylic acids Hydrocarbon derivatives Monoalkylamines Organic oxides Organofluorides
• Molecular Framework: Not available
• Substituents: Quinoline-3-carboxylic acid - Fluoroquinolone - Haloquinoline - Dihydroquinolone - Benzoxazine - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Aralkylamine - Alkyl aryl ether - Benzenoid - Pyridine - Aryl fluoride - Aryl halide - Heteroaromatic compound - Vinylogous amide - Alkanesulfonic acid - Sulfonyl - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Methanesulfonate - Amino acid or derivatives - Amino acid - Azacycle - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Ether - Organosulfur compound - Organic oxide - Organic oxygen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Primary amine - Organooxygen compound - Primary aliphatic amine - Organohalogen compound - Organofluoride - Organonitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Solubility in water: Completely soluble; Soluble in Dimethylformamide,Methanol; Slightly soluble in Ethanol
• Specific Rotation[α]: [α]D -62° (C=1,1mol/L NaOH)
• Melt Point(°C): 259 °C
• Molecular Weight: 414.400 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 414.09 Da
• Monoisotopic Mass: 414.09 Da
• Topological Polar Surface Area: 156.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 695.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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