PI(3,4,5)P3 18:0/20:4 - ≥95% , CAS No.799268-60-3

CAS: 799268-60-3 Cat. No.: S130398 Molecular Weight: 1214.99

GRADE & PURITY ≥95%

Synonyms

1D-1-O-(2-O-Arachidonoyl-1-O-stearoyl-sn-glycero-3-O-phospho)-myo-inositol 3,4,5-Trisphosphate | 18:0/20:4 PI(3,4,5)P3

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

PI(3,4,5)P3 (Phosphatidylinositol 3,4,5-trisphosphate) 18:0/20:4 is a synthetic, purified PI(3,4,5)P3 with stearoyl and arachidonoyl acyl groups.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.

Specifications

Synonyms

1D-1-O-(2-O-Arachidonoyl-1-O-stearoyl-sn-glycero-3-O-phospho)-myo-inositol 3, 4, 5-Trisphosphate | 18:0/20:4 PI(3, 4, 5)P3

Specifications & Purity

≥95%

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Molecular Weight: 1214.99

Chemical and Physical Properties

• Solubility: Solubility: H2O, <1 mg/mL ; MeOH:H2O (1:4), <1 mg/m
• Sensitivity: Moisture sensitive