GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.His Tag?His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein.≥98%(SDS-PAGE)
Expression System
HEK293
Accession #
Q9NQS3
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,His-Tag,≥98%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Purity
>98% SDS-PAGE.
Function
Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Specifications
Product Name
Recombinant Human Nectin-3 Protein, ＞98%(SDS-PAGE)
Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
71.1 kDa, under reducing conditions; 68.0 kDa, under non-reducing conditions.
Molecule Type
Protein
Storage and Shipping
Shape
Lyophilized
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.59mg/mL.
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -20℃ to -80℃ upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
Images
Recombinant Human Nectin-3 Protein (rp149161) - Protein Bioactivity Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
Recombinant Human Nectin-3 Protein (rp149161) - SDS-PAGE 2.5μg/lane of Recombinant Human Nectin-3 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 71.1 kDa under reducing conditions and 68.0 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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