RN-1 dihydrochloride - ≥97% , CAS No.1781835-13-9

CAS: 1781835-13-9 Cat. No.: R276429 Molecular Weight: 452.42 PubChem CID: 90488995

GRADE & PURITY ≥97%

Synonyms

1-(4-Methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenonedihydrochloride

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Overview

Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Specifications

Synonyms

1-(4-Methylpiperazin-1-yl)-2-[[(1R, 2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenonedihydrochloride

Specifications & Purity

≥97%

Biochemical and Physiological Mechanisms

Potent, cell-permeable LSD-1 inhibitor (IC 50 = 70 nM). Selective for LSD-1 versus MAO-A (IC 50 = 0.51\xa0μM) and MAO-B (IC 50 = 2.79\xa0μM).\xa0Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.

Storage

Store at -20°C, Desiccated

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥97%

Names and Identifiers

• Canonical Smiles: CN1CCN(CC1)C(=O)CNC2CC2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
• IUPAC Name: 1-(4-methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethanone;dihydrochloride
• InChIKey: WMHAFZOOUBPQRX-VSIGASKDSA-N
• INCHI: 1S/C23H29N3O2.2ClH/c1-25-11-13-26(14-12-25)23(27)16-24-22-15-21(22)19-7-9-20(10-8-19)28-17-18-5-3-2-4-6-18;;/h2-10,21-22,24H,11-17H2,1H3;2*1H/t21-,22+;;/m0../s1
• Isomeric SMILES: CN1CCN(CC1)C(=O)CN[C@@H]2C[C@H]2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
• PubChem CID: 90488995
• Molecular Weight: 452.42

Chemical and Physical Properties

• Solubility: DMSO: 8 mg/mL Water: 8 mg/mL