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· · COA & SDS available for every product · Same-day shipping on in-stock items SB 772077B dihydrochloride - ≥99%(HPLC) , CAS No.607373-46-6
Synonyms
(3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride
Storage
Room temperature,Desiccated
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Why this grade ≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
(3S)-1-[[2-(4-Amino-1, 2, 5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4, 5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride
Specifications & Purity
≥99%(HPLC)
Biochemical and Physiological Mechanisms
Potent Rho-kinase (ROCK) inhibitor (IC50value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent thanY-27632
Storage
Room temperature, Desiccated
Names and Identifiers Canonical Smiles CCN1C2=C(C=NC=C2C(=O)N3CCC(C3)N)N=C1C4=NON=C4N.Cl.Cl IUPAC Name [2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-7-yl]-[(3S)-3-aminopyrrolidin-1-yl]methanone;dihydrochloride InChIKey HSROPTGRSYJPJY-JZGIKJSDSA-N INCHI 1S/C15H18N8O2.2ClH/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11;;/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21);2*1H/t8-;;/m0../s1 Isomeric SMILES CCN1C2=C(C=NC=C2C(=O)N3CC[C@@H](C3)N)N=C1C4=NON=C4N.Cl.Cl PubChem CID 69157798 Molecular Weight 415.28
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data 3D Structure Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 41.53, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 41.53, Max Conc. mM: 100 Molecular Weight 415.300 g/mol XLogP3 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 3 Exact Mass 414.109 Da Monoisotopic Mass 414.109 Da Topological Polar Surface Area 142.000 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 508.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 3
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