≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 20 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Description
Silicon amine protocol (SLAP) reagents, in conjunction with aldehydes and ketones, formN-unprotected piperazines via photocatalytic cross-coupling with Ir[(ppy)2dtbbpy]PF6(747769). Heteroaromatic, aromatic, and aliphatic aldehydes are well tolerated, as are structurally and stereochemically complex SLAP reagents. This product was introduced in collaboration with theBode Research Groupand provides a tin-free alternative toSnAP(tin amine protocol) reagents for piperazine synthesis.
| Canonical Smiles | C[Si](C)(C)CN(CCN)CC1=CC=CC=C1 |
|---|---|
| IUPAC Name | N'-benzyl-N'-(trimethylsilylmethyl)ethane-1,2-diamine |
| InChIKey | OIVATBFWYNCAKW-UHFFFAOYSA-N |
| INCHI | 1S/C13H24N2Si/c1-16(2,3)12-15(10-9-14)11-13-7-5-4-6-8-13/h4-8H,9-12,14H2,1-3H3 |
| Isomeric SMILES | C[Si](C)(C)CN(CCN)CC1=CC=CC=C1 |
| PubChem CID | 122164959 |
| Molecular Weight | 236.44 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Phenylmethylamines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylmethylamines |
| Alternative Parents | Benzylamines Aralkylamines Trialkylamines Organic metalloid salts Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives Alkylsilanes |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Phenylmethylamine - Benzylamine - Aralkylamine - Tertiary aliphatic amine - Tertiary amine - Organic metalloid salt - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organic salt - Organosilicon compound - Alkylsilane - Organonitrogen compound - Primary aliphatic amine - Amine - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenylmethylamines. These are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine. |
| External Descriptors | Not available |
| Molecular Weight | 236.430 g/mol |
|---|---|
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 6 |
| Exact Mass | 236.171 Da |
| Monoisotopic Mass | 236.171 Da |
| Topological Polar Surface Area | 29.300 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 183.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yu Wu, Wenjie Zhang, Yalun Li, Xuning Feng, Zhuang Ma, Dongsheng Ren, Languang Lu, Gui-Liang Xu, Khalil Amine, Minggao Ouyang. (2023) Solid-state interphases design for high-safety, high-voltage and long-cyclability practical batteries via ethylene carbonate-free electrolytes. Energy Storage Materials, [PMID:] [10.1016/j.ensm.2023.103165] |
| 2. Pengbo Xue, Yue Yu, Hui Wang, Yonglei Cao, Bi Shi, Ya-nan Wang. (2023) Oxidized sodium lignosulfonate: A biobased chrome-free tanning agent for sustainable eco-leather manufacture. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2023.117916] |
| 3. Jia Ma, Jiang-Hua Zhang, Hua-Wei Zhang, Qian-Qian Du, Zi-Xuan Li, Zhi-Fei Yang, Sha-Sha Yang, Da-Yong Zhou. (2023) Highly effective synthesis of novel structured phospholipid emulsifiers using magnetically recyclable Fe3O4@SiO2/M (M = Zn or Al) composite. FOOD CHEMISTRY, [PMID:37678122] [10.1016/j.foodchem.2023.137313] |
| 4. Lu Liu, Suzhen Lei, Xiaoli Lin, Junfu Ji, Yanbo Wang, Baodong Zheng, Yi Zhang, Hongliang Zeng. (2023) Lotus seed resistant starch and sodium lactate regulate small intestinal microflora and metabolite to reduce blood lipid. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:36740125] [10.1016/j.ijbiomac.2023.123553] |
| 5. Songmao Zhang, Yichun Wang, Yawen Li, Manhui Wei, Keliang Wang. (2022) Sodium lignosulphonate decomposing accumulated byproducts of quasi-solid aluminum-air batteries. JOURNAL OF POWER SOURCES, [PMID:] [10.1016/j.jpowsour.2022.232088] |
| 6. Yunju Wang, Shunchao Ma, Hongyu Wang. (2022) Difluoro(oxalato)borate's Role in the Intercalation Behavior of Mixed Anions from Sulfolane. ChemSusChem, 16 (4): (e202201218). [PMID:36039804] [10.1002/cssc.202201218] |
| 7. Yimin Huang, Bing Wang, Jiapei Lv, Yingnan He, Hucai Zhang, Wenyan Li, Yongtao Li, Thomas Wågberg, Guangzhi Hu. (2022) Facile synthesis of sodium lignosulfonate/polyethyleneimine/sodium alginate beads with ultra-high adsorption capacity for Cr(VI) removal from water. JOURNAL OF HAZARDOUS MATERIALS, [PMID:35739785] [10.1016/j.jhazmat.2022.129270] |
| 8. Shasha Jiang, Weilin Qi, Cheng Ma, Tongyue Wu, Xiaoyu Li, Xingyue Chen, Shuitao Gao, Jinwan Qi, Yun Yan, Jianbin Huang. (2022) The high-concentration stable phase: The breakthrough of catanionic surfactant aqueous system. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.129120] |
| 9. Wang Zi-Qiang, Zhang Yue-Fei, Li Yan, Zhong Jin-Rong. (2022) Effect of sodium lignosulfonate/nano calcium carbonate composite filler on properties of isotactic polypropylene. POLYMER BULLETIN, 80 (3): (3103-3117). [PMID:] [10.1007/s00289-022-04209-y] |
| 10. Xiao Xiao, Yan Qiao, Zhirui Xu, Tongyue Wu, Yunxue Wu, Zhe Ling, Yun Yan, Jianbin Huang. (2021) Enzyme-Responsive Aqueous Two-Phase Systems in a Cationic–Anionic Surfactant Mixture. LANGMUIR, [PMID:34714092] [10.1021/acs.langmuir.1c02303] |
| 11. Weijun Zhou, Minfeng Chen, Qinghua Tian, Jizhang Chen, Xinwu Xu, Xiang Han, Junling Xu. (2021) Stabilizing zinc deposition with sodium lignosulfonate as an electrolyte additive to improve the life span of aqueous zinc-ion batteries. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:34090026] [10.1016/j.jcis.2021.05.134] |
| 12. Jiongjiong Li, Xiaona Li, Fudong Zhang, Wei Zhang, Jianzhang Li. (2021) Facile design of tough, strong, and UV-shielding soy protein-based composite films. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2021.113474] |
| 13. Chunlei Li, Peng Wang, Shiyou Li, Dongni Zhao, Qiuping Zhao, Haining Liu, Xiaoling Cui. (2018) Active Mechanism of the Interphase Film-Forming Process for an Electrolyte Based on a Sulfolane Solvent and a Chelato-Borate Complex. ACS Applied Materials & Interfaces, [PMID:29900736] [10.1021/acsami.8b05125] |
| 14. Li Jian, Meng Pengyu, Zhou Hongming. (2018) Regularities of ionic solvation and association of lithium difluoro(oxalate)borate in dimethyl carbonate and sulfolane solvent systems. IONICS, 24 (7): (2147-2155). [PMID:] [10.1007/s11581-018-2463-0] |
| 15. Guanjie Li, Dengpan Dong, Dmitry Bedrov, Qinqin Cai, Haojun Wu, Zixing Wang, Jilei Liu, Kang Xu, Lidan Xing, Weishan Li. (2025) Correlating electrode nano-confinement to interphase chemistry. Joule, [PMID:] [10.1016/j.joule.2025.101874] |
| 16. Zhiwei Qiu, Hailan Wang, Ruobin Dai, Zhiwei Wang. (2025) Enhancing Silica Scaling Resistance and Perm-Selectivity of Reverse Osmosis Membranes via Increased Charge Density and Suppressed Coordination Capacity. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:40052783] [10.1021/acs.est.4c13117] |
| 17. Ziwei Wu, Yiyang Chen, Yuan Peng, Haozhe Xue, Yongxin Yao, Shimeng Yang, Chengyuan Pan, Dayu Zhang, Yongjian Xie. (2025) Sodium-lignosulfonate-conjugated metal–organic frameworks as dual-stimulus-responsive carriers for improved pesticide targeting. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39978517] [10.1016/j.ijbiomac.2025.141275] |
| 18. Lu Liu, Suzhen Lei, Xiaoli Lin, David Mahoudjro Bodjrenou, Yi Zhang, Baodong Zheng, Hongliang Zeng. (2025) Synergistic regulation of colon microflora and metabolic environment by resistant starch and sodium lactate in hyperlipidemic rats. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:40074132] [10.1016/j.ijbiomac.2025.141933] |
| 19. Feixue Gong, Na Du, Wanguo Hou. (2025) Estimation of surface free energy and solubility parameters of solid ionic surfactants. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:40915289] [10.1016/j.jcis.2025.138914] |
| 20. Pengcheng Shi, Xin Liang, Kun Xu, Yi Sun, Sheng Cheng, Chunhua Chen, Hongfa Xiang. (2020) Sulfone-assisted-NH4I as electrolyte additive with synergistic dissolution and catalysis effects on reducing the activation voltage of Li2S cathode. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2020.125608] |
