T16Ainh-A01 - Moligand™, 10 mM in DMSO , CAS No.552309-42-9

CAS: 552309-42-9 Cat. No.: T1493172 Molecular Weight: 416.52 EC Number: 803-943-3 PubChem CID: 135460621

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC 50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: CCC1=C(N=C(NC1=O)SCC(=O)NC2=NC(=CS2)C3=CC=C(C=C3)OC)C
• WGK Germany: 3
• PubChem CID: 135460621
• Molecular Weight: 416.52

References

1. Jiaao Shen, Zijia Man, Weiwei Li, Mengqi Guo, Zefeng Xiang, Long Ma, Xianjiang Kang, Shuai Guo.  (2025)  Natural isoflavone sophoricoside emerges as a therapeutic candidate for lung cancer targeting TMEM16A ion channel.  PHYTOMEDICINE,      [PMID:41014666] [10.1016/j.phymed.2025.157289]

2. Xue Bai, Yinuo Liu, Yuchen Cao, Zhouye Ma, Yue Chen, Shuai Guo.  (2024)  Exploring the potential of cryptochlorogenic acid as a dietary adjuvant for multi-target combined lung cancer treatment.  PHYTOMEDICINE,      [PMID:39053244] [10.1016/j.phymed.2024.155907]