Topotecan hydrochloride hydrate - Moligand™, ≥98%(HPLC) , CAS No.123948-87-8(free base)

CAS: 123948-87-8(free base) Cat. No.: T166659 Molecular Weight: 421.45 (anhydrous free base basis) EC Number: 687-471-1
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
10mg
T166659-10mg
2
$150.90
50mg
T166659-50mg
2
$407.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells.

Specifications

Specifications & Purity
Moligand™, ≥98%(HPLC)
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Purity
≥98%(HPLC)
Names and Identifiers
Molecular Weight 421.45 (anhydrous free base basis)

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
HIF1A Tchem Hypoxia-inducible factor 1-alpha (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TOP1 Tclin DNA topoisomerase 1 (7 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I2007048Certificate of AnalysisJun 19, 2024 T166659
I2007047Certificate of AnalysisJun 19, 2024 T166659
E2308085Certificate of AnalysisMay 20, 2023 T166659
C2324880Certificate of AnalysisMar 30, 2023 T166659
Chemical and Physical Properties
SolubilityTopotecan hydrochloride hydrate is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml
Sensitivitylight sensitive
Solution Calculators
Reviews

Customer Reviews

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