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Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
WAY-100635 is a potent and selective 5-HT 1A Receptor antagonist with a pIC 50 of 8.87, an apparent pA 2 of 9.71.WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D 4 receptor agonist.
| Isomeric SMILES | COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4CCCCC4 |
|---|---|
| Alternate CAS | 162760-96-5;634908-75-1;1092679-51-0 |
| MeSH Entry Terms | cyclohexanecarboxamide, N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-2-pyridinyl-;N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide;WAY 100,635;WAY 100635;WAY-100,635;WAY-100635;WAY100,635 |
| Molecular Weight | 422.56 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →| 1. Lina Ruan, Kaiyu Guan, Yue Wang, Ming Gu, Yue Chen, Lisha Cai, Ruixuan Ye, Zhengwei Huang, Anqi Guo, Zhengkang Su, Xi Li, Jianchun Pan. (2022) Baicalein exerts anxiolytic and antinociceptive effects in a mouse model of posttraumatic stress disorder: Involvement of the serotonergic system and spinal delta-opioid receptors. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, [PMID:36462602] [10.1016/j.pnpbp.2022.110689] |
| 2. Rong Xiong, Wei Zhao, Xi Chen, Tian Li, Haiyin Li, Yan Li, Wangshang Shen, Ping Chen. (2019) Pharmacological characterization of the 5-HT1A receptor of Bombyx mori and its role in locomotion. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, [PMID:30690153] [10.1016/j.cbpa.2019.01.020] |
| 3. Ruobing Bai, Hongyi Xian, Yu Feng, Xiyun Huang, Shiyue Tang, Zhiming Li, Long Zhang, Yizhou Zhong, Wanyan Wu, Jiangpeng Tang, Chudan Gao, Li Yan, Xinguang Zhong, Da Chen, Zhenlie Huang. (2025) Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:40957726] [10.1021/acs.est.5c07209] |
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