Shown to selectively activate group II mGlu receptors in transfected HEK293 cells at nanomolar concentrations. Attenuates cAMP formation in mouse cortical slices expressing mGlu2and mGlu3receptors.
This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
External Descriptors
quinolinemonocarboxylic acid - dihydroxyquinoline
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1.Li Yueyue, Li Jingjie, Shi Yuhuan, Zhou Xuhui, Feng Wanqing, Han Lu, Ma Daqing, Jiang Hong, Yuan Yongfang. (2022) Urinary Aromatic Amino Acid Metabolites Associated With Postoperative Emergence Agitation in Paediatric Patients After General Anaesthesia: Urine Metabolomics Study. Frontiers in Pharmacology, [PMID:35928271][10.3389/fphar.2022.932776]
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