≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature,Cool Ships FedEx DG Service Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 504752021 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504752021 |
| Canonical Smiles | C1=CC(=CC=C1F)F |
| IUPAC Name | 1,4-difluorobenzene |
| InChIKey | QUGUFLJIAFISSW-UHFFFAOYSA-N |
| INCHI | 1S/C6H4F2/c7-5-1-2-6(8)4-3-5/h1-4H |
| Isomeric SMILES | C1=CC(=CC=C1F)F |
| WGK Germany | 3 |
| RTECS | CZ5658000 |
| UN Number | 1993 |
| Molecular Weight | 114.09 |
| Beilstein | 1904541 |
| Reaxy-Rn | 1904541 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1904541&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Halobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Fluorobenzenes |
| Alternative Parents | Aryl fluorides Organofluorides Hydrofluorocarbons Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Fluorobenzene - Aryl halide - Aryl fluoride - Hydrofluorocarbon - Hydrocarbon derivative - Organofluoride - Organohalogen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as fluorobenzenes. These are compounds containing one or more fluorine atoms attached to a benzene ring. |
| External Descriptors | difluorobenzene |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2602132 | Certificate of Analysis | Oct 29, 2025 | D113734 |
| K2512561 | Certificate of Analysis | Oct 29, 2025 | D113734 |
| K2512562 | Certificate of Analysis | Oct 29, 2025 | D113734 |
| K2512566 | Certificate of Analysis | Oct 29, 2025 | D113734 |
| K2512570 | Certificate of Analysis | Oct 29, 2025 | D113734 |
| K21251061 | Certificate of Analysis | Sep 08, 2025 | D113734 |
| C2506191 | Certificate of Analysis | Mar 11, 2025 | D113734 |
| C2506143 | Certificate of Analysis | Mar 08, 2025 | D113734 |
| C2512281 | Certificate of Analysis | Mar 08, 2025 | D113734 |
| L1918109 | Certificate of Analysis | Oct 20, 2023 | D113734 |
| H1510255 | Certificate of Analysis | Apr 12, 2023 | D113734 |
| I2202158 | Certificate of Analysis | Aug 07, 2021 | D113734 |
| I2321058 | Certificate of Analysis | Aug 07, 2021 | D113734 |
| K2419112 | Certificate of Analysis | Aug 07, 2021 | D113734 |
| Solubility | Insoluble in water, soluble in ethanol, etc. |
|---|---|
| Sensitivity | Moisture sensitive |
| Refractive Index | 1.44-1.442 |
| Flash Point(°F) | 35.6 °F |
| Flash Point(°C) | 2℃ |
| Boil Point(°C) | 88°C-89°C |
| Melt Point(°C) | -13°C |
| Molecular Weight | 114.090 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 114.028 Da |
| Monoisotopic Mass | 114.028 Da |
| Topological Polar Surface Area | 0.000 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 54.900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Zhu Mingming, Li Bingfei, Ma Xiao, Huang Cong, Wu Rui, Zhu Weiwei, Li Xiaoting, Liang Zhaofeng, Deng Feifei, Zhu Jianyun, Xie Wei, Yang Xue, Jiang Ye, Wang Shijia, Wu Jieshu, Geng Shanshan, Xie Chunfeng, Zhong Caiyun, Liu Haiyan. (2016) Folic Acid Protected Neural Cells Against Aluminum-Maltolate-Induced Apoptosis by Preventing miR-19 Downregulation. NEUROCHEMICAL RESEARCH, 41 (8): (2110-2118). [PMID:27113042] [10.1007/s11064-016-1926-9] |
| 2. Zhu Mingming, Huang Cong, Ma Xiao, Wu Rui, Zhu Weiwei, Li Xiaoting, Liang Zhaofeng, Deng Feifei, Zhu Jianyun, Xie Wei, Yang Xue, Jiang Ye, Wang Shijia, Wu Jieshu, Geng Shanshan, Xie Chunfeng, Zhong Caiyun. (2016) Modulation of miR-19 in Aluminum-Induced Neural Cell Apoptosis. JOURNAL OF ALZHEIMERS DISEASE, 50 (4): (1149-1162). [PMID:26836165] [10.3233/JAD-150763] |
| 3. Ma Baochen, Zhang Haikuo, Li Ruhong, Zhang Shuoqing, Chen Long, Zhou Tao, Wang Jinze, Zhang Ruixin, Ding Shouhong, Xiao Xuezhang, Deng Tao, Chen Lixin, Fan Xiulin. (2024) Molecular-docking electrolytes enable high-voltage lithium battery chemistries. Nature Chemistry, [PMID:39009795] [10.1038/s41557-024-01585-y] |
| 4. Jia Guo, Sichen Gu, Wanli Nie, Bo Long, Sergey Ryazantsev, Sergei Malyshev, Juan Li, Shaohua Guo, Chuan Wu. (2025) Mixed Electrolyte Enabling Ultrafast Mass Transport and Compatibility with Polypropylene Separator for Stable and Low-Cost Aluminum Ion Battery. ADVANCED MATERIALS, [PMID:40025955] [10.1002/adma.202419865] |
