1-N-(4,4'-Dimethoxytrityl)-D-(+)-biotin - ≥95% , CAS No.144095-63-6

CAS: 144095-63-6 Cat. No.: N357919 Molecular Weight: 546.68 PubChem CID: 11592031

GRADE & PURITY ≥95%

Synonyms

D-Biotin 4,4′-dimethoxytrityl ester | DMT-Biotin

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

Product description

DMT-Biotin is a chemical compound used in the synthesis of biotinylated oligonucleotides, a class of molecules with various applications in biomedical research. It is a derivative of biotin, a small molecule that binds with high affinity to streptavidin, allowing for specific and efficient detection or purification of biotinylated molecules. DMT-Biotin contains a dimethoxytrityl (DMT) group, which provides protection to the biotin moiety during synthesis and purification. This compound is commonly used for the synthesis of biotinylated oligonucleotides for applications in DNA sequencing, PCR, microarrays, and other molecular biology techniques. DMT-Biotin is a useful tool for researchers in the fields of genomics and proteomics.

Specifications

Synonyms

D-Biotin 4, 4′-dimethoxytrityl ester | DMT-Biotin

Specifications & Purity

≥95%

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%

Names and Identifiers

• Pubchem Sid: 504766568
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504766568
• Canonical Smiles: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)N4C5CSC(C5NC4=O)CCCCC(=O)O
• IUPAC Name: 5-[(3aR,6S,6aS)-3-[bis(4-methoxyphenyl)-phenylmethyl]-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]pentanoic acid
• InChIKey: RMWVJZXKPGLZEJ-YCVJPRETSA-N
• INCHI: 1S/C31H34N2O5S/c1-37-24-16-12-22(13-17-24)31(21-8-4-3-5-9-21,23-14-18-25(38-2)19-15-23)33-26-20-39-27(29(26)32-30(33)36)10-6-7-11-28(34)35/h3-5,8-9,12-19,26-27,29H,6-7,10-11,20H2,1-2H3,(H,32,36)(H,34,35)/t26-,27-,29-/m0/s1
• Isomeric SMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)N4[C@H]5CS[C@H]([C@H]5NC4=O)CCCCC(=O)O
• PubChem CID: 11592031
• Molecular Weight: 546.68

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Triphenyl compounds

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Triphenyl compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Triphenyl compounds
• Alternative Parents: Biotin and derivatives Anisoles Medium-chain fatty acids Methoxybenzenes Phenoxy compounds Thienoimidazolidines Alkyl aryl ethers Heterocyclic fatty acids Thia fatty acids Imidazolidinones Thiolanes Thiophenes Ureas Monocarboxylic acids and derivatives Azacyclic compounds Dialkylthioethers Carboxylic acids Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Triphenyl compound - Biotin_derivative - Biotin - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Thienoimidazolidine - Medium-chain fatty acid - Alkyl aryl ether - Heterocyclic fatty acid - Thia fatty acid - Monocyclic benzene moiety - Imidazolidinone - Fatty acyl - Fatty acid - Thiophene - Thiolane - Imidazolidine - Urea - Thioether - Organoheterocyclic compound - Dialkylthioether - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Azacycle - Ether - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Moisture sensitive.
• Molecular Weight: 546.700 g/mol
• XLogP3: 5.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 546.219 Da
• Monoisotopic Mass: 546.219 Da
• Topological Polar Surface Area: 113.000 Ų
• Heavy Atom Count: 39
• Formal Charge: 0
• Complexity: 796.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1