2-Amino-4-nitrophenol - ≥98% , CAS No.99-57-0

CAS: 99-57-0 Cat. No.: A107508 Molecular Weight: 154.12 Beilstein Registry Number: 776533 EC Number: 202-767-9
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
4-Nitro-2-aminophenol | 1-Amino-2-hydroxy-5-nitrobenzene | NCI-C55958 | 2-Amino-4-nitrofenol [Czech] | FT-0619188 | 1-Hydroxy-2-amino-4-nitrobenzene | 2-Amino-4-nitrophenol, >=99.0% (NT) | BRN 0776533 | G501UCI6T9 | 2-Amino-4-nitrofenol | 2-AMINO-4-NITROP
Storage
Room temperature
Shipped In
FedEx DG Service
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
A107508-5g
5
$9.90
25g
A107508-25g
3
$23.90
100g
A107508-100g
1
$49.90
500g
A107508-500g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$165.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
4-Nitro-2-aminophenol | 1-Amino-2-hydroxy-5-nitrobenzene | NCI-C55958 | 2-Amino-4-nitrofenol [Czech] | FT-0619188 | 1-Hydroxy-2-amino-4-nitrobenzene | 2-Amino-4-nitrophenol, >=99.0% (NT) | BRN 0776533 | G501UCI6T9 | 2-Amino-4-nitrofenol | 2-AMINO-4-NITROP
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
FedEx DG Service
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥98%
Names and Identifiers
Pubchem Sid488194478
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488194478
Canonical SmilesC1=CC(=C(C=C1[N+](=O)[O-])N)O
IUPAC Name2-amino-4-nitrophenol
InChIKeyVLZVIIYRNMWPSN-UHFFFAOYSA-N
INCHI1S/C6H6N2O3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H,7H2
Isomeric SMILES C1=CC(=C(C=C1[N+](=O)[O-])N)O
WGK Germany 2
RTECS SJ6300000
UN Number 2811
Packing Group I
Molecular Weight 154.12
Beilstein 776533
Reaxy-Rn 776533
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=776533&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassPhenols
SubclassNitrophenols
Intermediate Tree Nodes Not available
Direct ParentNitrophenols
Alternative Parents Nitrobenzenes  o-Aminophenols  Nitroaromatic compounds  Aniline and substituted anilines  1-hydroxy-2-unsubstituted benzenoids  Propargyl-type 1,3-dipolar organic compounds  Organic oxoazanium compounds  Primary amines  Organopnictogen compounds  Organooxygen compounds  Organic zwitterions  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Nitrophenol - Nitrobenzene - Aminophenol - O-aminophenol - Nitroaromatic compound - Aniline or substituted anilines - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - C-nitro compound - Organic nitro compound - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Primary amine - Organooxygen compound - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic zwitterion - Organic nitrogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as nitrophenols. These are compounds containing a nitrophenol moiety, which consists of a benzene ring bearing both a hydroxyl group and a nitro group on two different ring carbon atoms.
External Descriptors C-nitro compound - phenols
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLH Tchem DNA polymerase eta (21678 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Skin (286 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Impa1 Inositol monophosphatase 1 (16203 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
I2525056Certificate of AnalysisOct 14, 2025 A107508
J2515156Certificate of AnalysisOct 14, 2025 A107508
I2122029Certificate of AnalysisJun 15, 2023 A107508
K1918143Certificate of AnalysisJun 06, 2023 A107508
E2126032Certificate of AnalysisMar 08, 2023 A107508
B2505062Certificate of AnalysisJan 13, 2023 A107508
C23111199Certificate of AnalysisJan 13, 2023 A107508
C23111204Certificate of AnalysisJan 13, 2023 A107508
C23111205Certificate of AnalysisJan 13, 2023 A107508
C23111209Certificate of AnalysisJan 13, 2023 A107508
C23111213Certificate of AnalysisJan 13, 2023 A107508
C23111221Certificate of AnalysisJan 13, 2023 A107508
C23111232Certificate of AnalysisJan 13, 2023 A107508
E2311120Certificate of AnalysisJan 13, 2023 A107508
H1808093Certificate of AnalysisFeb 16, 2022 A107508

Show more ⌵

Chemical and Physical Properties
SolubilitySlightly soluble in water; Very soluble in Alcohol; Soluble in Methanol,Ether
Flash Point(°F)212 °F
Flash Point(°C)100 °C
Melt Point(°C)140°C-148°C
Molecular Weight154.120 g/mol
XLogP31.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass154.038 Da
Monoisotopic Mass154.038 Da
Topological Polar Surface Area92.100 Ų
Heavy Atom Count11
Formal Charge0
Complexity156.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Fu Fengping, He Qian, Zhao Shizheng, Zhu Ting, Liao Fang.  (2021)  Synthesis of photoluminescent m-phenylenediamine-Rhodamine B copolymer dots: selective ultrahigh photocatalytic performance for catalytic reduction of nitro-compound.  RESEARCH ON CHEMICAL INTERMEDIATES,  47  (10): (4173-4192).  [PMID:] [10.1007/s11164-021-04512-9]
2. Fu Yang, Jin Wang, Shuying Gao, Shijian Zhou, Yan Kong.  (2020)  Record-high catalytic hydrogenated activity in nitroarenes reduction derived from in-situ nascent active metals enabled by constructing bimetallic phosphate.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2020.110873]
3. Lala Rukh Sidra, Guofei Chen, Nafeesa Mushtaq, Kai Ma, Beenish Bashir, Xingzhong Fang.  (2018)  Processable poly(benzoxazole imide)s derived from asymmetric benzoxazole diamines containing 4-phenoxy aniline: synthesis, properties and the isomeric effect.  Polymer Chemistry,  (20): (2785-2796).  [PMID:] [10.1039/C8PY00382C]
4. Kun Hu, Pei Chen, Qiang Weng, Dingqian Shi, Ran Chen, Xinbing Chen, Zhongwei An.  (2015)  Preparation and properties of lateral monofluoro-substituted benzoxazole-based mesogenic compounds.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2015.1069412]
5. Kun Hu, Pei Chen, Qiang Weng, Dingqian Shi, Ran Chen, Xinbing Chen, Zhongwei An.  (2015)  Improved mesophase stability of benzoxazole derivatives via dipole moment modification.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2015.1084656]
6. Pei Chen, Yiwei Xu, Weisong Du, Guangping Zhang, Xinbing Chen, Zhongwei An.  (2014)  New Mesogenic Compounds Containing a Terminal-Substituted Benzoxazole Unit.  MOLECULAR CRYSTALS AND LIQUID CRYSTALS,      [PMID:] [10.1080/15421406.2013.837997]
7. Yiwei Xu, Xinbing Chen, Fengqi Zhao, Xuezhong Fan, Pei Chen, Zhongwei An.  (2013)  Synthesis and properties of substituted benzoxazole-terminated liquid crystals.  LIQUID CRYSTALS,      [PMID:] [10.1080/02678292.2012.735709]
Solution Calculators
Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.