≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2-Chloro-4-cyanopyridine is an intermediate used to prepare pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). It is also used to synthesize pyridinyl-tetrazoles as scaffold to identify matrix MMP-13 inhibitors for treatment of osteoarthritis.
| Pubchem Sid | 488190347 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488190347 |
| Canonical Smiles | C1=CN=C(C=C1C#N)Cl |
| IUPAC Name | 2-chloropyridine-4-carbonitrile |
| InChIKey | QRXBTPFMCTXCRD-UHFFFAOYSA-N |
| INCHI | 1S/C6H3ClN2/c7-6-3-5(4-8)1-2-9-6/h1-3H |
| Isomeric SMILES | C1=CN=C(C=C1C#N)Cl |
| WGK Germany | 3 |
| Molecular Weight | 138.55 |
| Beilstein | 22(5)2,302 |
| Reaxy-Rn | 113927 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=113927&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Halopyridines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 2-halopyridines |
| Alternative Parents | Aryl chlorides Heteroaromatic compounds Nitriles Azacyclic compounds Organopnictogen compounds Organochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | 2-halopyridine - Aryl halide - Aryl chloride - Heteroaromatic compound - Azacycle - Nitrile - Carbonitrile - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as 2-halopyridines. These are organic compounds containing a pyridine ring substituted at the 2-position by a halogen atom. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2209199 | Certificate of Analysis | May 12, 2025 | C107767 |
| H2209212 | Certificate of Analysis | May 12, 2025 | C107767 |
| H2209219 | Certificate of Analysis | May 12, 2025 | C107767 |
| G1919067 | Certificate of Analysis | Mar 04, 2025 | C107767 |
| K2111508 | Certificate of Analysis | Aug 21, 2024 | C107767 |
| K2111509 | Certificate of Analysis | Aug 21, 2024 | C107767 |
| K2111542 | Certificate of Analysis | Aug 21, 2024 | C107767 |
| Solubility | soluble in MeOH |
|---|---|
| Boil Point(°C) | 106°C/15mmHg |
| Melt Point(°C) | 72°C |
| Molecular Weight | 138.550 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 137.998 Da |
| Monoisotopic Mass | 137.998 Da |
| Topological Polar Surface Area | 36.700 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 137.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
