2′-Deoxy-5′-O-DMT-N6-methyladenosine - ≥98% , CAS No.98056-69-0

CAS: 98056-69-0 Cat. No.: D337646 Molecular Weight: 567.63 PubChem CID: 10897065

GRADE & PURITY ≥98%

Synonyms

(2R,3S,5R)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-5-[6-(methylamino)-9H-purin-9-yl]oxolan-3-ol | 5'-O-(DIMETHOXYTRITYL)-N6-METHYL-2'-DEOXYADENOSINE | 5'-O-DMT-N6-Me-2'-dA | (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(methylam

Storage

Room temperature

Shipped In

Normal

Overview

application：

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-methyladenosine is a 5’-O-(4,4'-Dimethoxytriphenylmethy) substitued derivative of the 2’-deoxy N-methyl analogue of Adenosine. It is used in the preparation of oligonucleotides containing N6-methyladenine residues in the GATC site.

Specifications

Synonyms

(2R, 3S, 5R)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-5-[6-(methylamino)-9H-purin-9-yl]oxolan-3-ol | 5'-O-(DIMETHOXYTRITYL)-N6-METHYL-2'-DEOXYADENOSINE | 5'-O-DMT-N6-Me-2'-dA | (2R, 3S, 5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(methylam

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.

Storage

Room temperature

Shipped In

Normal

Action Type

ACTIVATOR

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488196899
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488196899
• Canonical Smiles: CNC1=C2C(=NC=N1)N(C=N2)C3CC(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O
• IUPAC Name: (2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-[6-(methylamino)purin-9-yl]oxolan-3-ol
• InChIKey: OKZZBPBWGABLJR-UPRLRBBYSA-N
• INCHI: 1S/C32H33N5O5/c1-33-30-29-31(35-19-34-30)37(20-36-29)28-17-26(38)27(42-28)18-41-32(21-7-5-4-6-8-21,22-9-13-24(39-2)14-10-22)23-11-15-25(40-3)16-12-23/h4-16,19-20,26-28,38H,17-18H2,1-3H3,(H,33,34,35)/t26-,27+,28+/m0/s1
• Isomeric SMILES: CNC1=C2C(=NC=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O
• PubChem CID: 10897065
• Molecular Weight: 567.63

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Triphenyl compounds

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Triphenyl compounds
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Triphenyl compounds
• Alternative Parents: Purine 2'-deoxyribonucleosides 6-alkylaminopurines Benzylethers Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Oxolanes Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Dialkyl ethers Azacyclic compounds Hydrocarbon derivatives Amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Triphenyl compound - Purine 2'-deoxyribonucleoside - Purine nucleoside - 6-alkylaminopurine - 6-aminopurine - Benzylether - Imidazopyrimidine - Purine - Anisole - Phenoxy compound - Phenol ether - Methoxybenzene - Aminopyrimidine - Alkyl aryl ether - Imidolactam - Pyrimidine - Monocyclic benzene moiety - N-substituted imidazole - Azole - Heteroaromatic compound - Imidazole - Oxolane - Secondary alcohol - Ether - Dialkyl ether - Organoheterocyclic compound - Oxacycle - Azacycle - Organic oxygen compound - Alcohol - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as triphenyl compounds. These are aromatic compounds containing a triphenyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 567.600 g/mol
• XLogP3: 4.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 10
• Exact Mass: 567.248 Da
• Monoisotopic Mass: 567.248 Da
• Topological Polar Surface Area: 113.000 Ų
• Heavy Atom Count: 42
• Formal Charge: 0
• Complexity: 808.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1