2'-O-Methylguanosine - Moligand™, 10 mM in DMSO , CAS No.2140-71-8

CAS: 2140-71-8 Cat. No.: O1500465 Molecular Weight: 297.27
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Argon charged,Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Status
Price
Qty
1ml
O1500465-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Argon charged, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)CO)O
Molecular Weight 297.27
Reaxy-Rn 11759216
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11759216&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α]-55° (C=1,1mol/L NaOH)
Melt Point(°C)236°C
Citations of This Product
References
1. Sirui Zhu, Yuanyuan Li, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu.  (2023)  The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis.  DEVELOPMENTAL CELL,      [PMID:37977150] [10.1016/j.devcel.2023.10.014]
2. Ziyi Wang, Ting Zou, Shitao Feng, Fengshou Wu, Juan Zhang.  (2023)  Boronic acid-functionalized magnetic porphyrin-based covalent organic framework for selective enrichment of cis-diol-containing nucleosides.  ANALYTICA CHIMICA ACTA,      [PMID:37709444] [10.1016/j.aca.2023.341691]
3. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin.  (2023)  A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L..  Genes,  14  (6): (1287).  [PMID:37372467] [10.3390/genes14061287]
4. Yu-Nan Chen, Xu-Yang Shen, Yue Yu, Chen-Yu Xue, Ying-Lin Zhou, Xin-Xiang Zhang.  (2023)  In-source fragmentation of nucleosides in electrospray ionization towards more sensitive and accurate nucleoside analysis.  ANALYST,  148  (7): (1500-1506).  [PMID:36883656] [10.1039/D3AN00047H]
5. Shitao Feng, An Zhang, Fengshou Wu, Xiaogang Luo, Juan Zhang.  (2022)  Boronic acid grafted metal-organic framework for selective enrichment of cis-diol-containing compounds.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:35809521] [10.1016/j.chroma.2022.463281]
6. Yu-Fang Ma, Fang Yuan, Yue Yu, Ying-Lin Zhou, Xin-Xiang Zhang.  (2019)  Synthesis of a pH-Responsive Functional Covalent Organic Framework via Facile and Rapid One-Step Postsynthetic Modification and Its Application in Highly Efficient N1-Methyladenosine Extraction.  ANALYTICAL CHEMISTRY,      [PMID:31813221] [10.1021/acs.analchem.9b04600]
7. Jia-Cheng Liu, Lin-Da Zhang, Yue Liu, Tian-Qi Zhou, Bin Lai, Ce Wang, Jia-Nan Yan, Hai-Tao Wu.  (2024)  Modification of gel properties of Meretrix meretrix (clam) with polysaccharides: physical characterization and interaction mechanism.  JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE,      [PMID:39364803] [10.1002/jsfa.13937]
8. Deng Dehai, Qin Yichao, Lin Xiuying, Chu Meng, Lv Daizhu, Lin Huan.  (2025)  Unveiling transfer RNA modifications of oil palm and their dynamic changes during fruit ripening.  BMC PLANT BIOLOGY,  25  (1): (1-17).  [PMID:40155815] [10.1186/s12870-025-06426-9]
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