5-Amino-8-hydroxyquinoline Dihydrochloride - ≥98% , CAS No.21302-43-2

CAS: 21302-43-2 Cat. No.: A151249 Molecular Weight: 233.09 EC Number: 627-849-5 PubChem CID: 16211947

GRADE & PURITY ≥98%

Synonyms

SY045909 | A1005 | 5-Amino-8-hydroxyquinoline.2 hydrochloride | AKOS015844933 | 4-chloro-alpha-cyclopropylbenzylalcohol | 5-Amino-8-hydroxyquinoline.2HCl | 5-aminoquinolin-8-ol dihydrochloride | DTXSID60583526 | 5-Amino-8-hydroxyquinoline DiHCl | SCHEMBL3

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

5-Amino-8-hydroxyquinoline dihydrochloride was used in synthesis of: . 5-acetamido-8-hydroxyquinoline hydrochloride . 5-(p-tolylsulfonylimino)quinolin-8-one . 5,8-quinolinesemiquinone via ferric chloride oxidation

Specifications

Synonyms

SY045909 | A1005 | 5-Amino-8-hydroxyquinoline.2 hydrochloride | AKOS015844933 | 4-chloro-alpha-cyclopropylbenzylalcohol | 5-Amino-8-hydroxyquinoline.2HCl | 5-aminoquinolin-8-ol dihydrochloride | DTXSID60583526 | 5-Amino-8-hydroxyquinoline DiHCl | SCHEMBL3

Specifications & Purity

≥98%

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488199136
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488199136
• Canonical Smiles: C1=CC2=C(C=CC(=C2N=C1)O)N.Cl.Cl
• IUPAC Name: 5-aminoquinolin-8-ol;dihydrochloride
• InChIKey: VTQDJAUGGZFPOI-UHFFFAOYSA-N
• INCHI: 1S/C9H8N2O.2ClH/c10-7-3-4-8(12)9-6(7)2-1-5-11-9;;/h1-5,12H,10H2;2*1H
• Isomeric SMILES: C1=CC2=C(C=CC(=C2N=C1)O)N.Cl.Cl
• WGK Germany: 3
• PubChem CID: 16211947
• Molecular Weight: 233.09
• Reaxy-Rn: 3915104

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Quinolines and derivatives
      • Subclass Aminoquinolines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Quinolines and derivatives
• Subclass: Aminoquinolines and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminoquinolines and derivatives
• Alternative Parents: Hydroxyquinolines 8-hydroxyquinolines 1-hydroxy-2-unsubstituted benzenoids Pyridinium derivatives Heteroaromatic compounds Azacyclic compounds Organooxygen compounds Organic zwitterions Organic chloride salts Hydrocarbon derivatives Amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Aminoquinoline - Hydroxyquinoline - 8-hydroxyquinoline - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyridine - Pyridinium - Benzenoid - Heteroaromatic compound - Azacycle - Organic chloride salt - Organic zwitterion - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organic salt - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as aminoquinolines and derivatives. These are organic compounds containing an amino group attached to a quinoline ring system.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Air Sensitive
• Melt Point(°C): 279°C(dec.)(lit.)
• Molecular Weight: 233.090 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 232.017 Da
• Monoisotopic Mass: 232.017 Da
• Topological Polar Surface Area: 59.100 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 163.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Hongwei Luo, Yaoyao Zhao, Dongqin He, Qing Ji, Ying Cheng, Daoyong Zhang, Xiangliang Pan.  (2019)  Hydroxylamine-facilitated degradation of rhodamine B (RhB) and p-nitrophenol (PNP) as catalyzed by Fe@Fe2O3 core-shell nanowires.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2019.02.136]

2. Zhu Weijie, Lin Yu-Chang, Cong Jianlong, Zhao Mengting, Li Jiahao, Hao Cong, Jia Jun, Wang Xinlu, Huang Yunhui, Lin Yan-Gu, Yang Gang, Yao Fen, Liang Hanfeng.  (2026)  Reverse hydrogen spillover accelerates electrocatalytic nitrate reduction to ammonia on Ru/WO3-x in acidic media.  Nature Communications,      [PMID:41698935] [10.1038/s41467-026-69335-x]