≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
5-Methyltetrahydrofolic acid disodium salt is the sodium salt form of 5-methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid disodium salt is a substrate and a cofactor used by 5-methyl-THF-homocysteine S-methyltransferase for regenerating methionine from homocysteine. 5-Methyltetrahydrofolic acid disodium salt is a folate derivative.
| Canonical Smiles | CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] |
|---|---|
| IUPAC Name | disodium;2-[[4-[(2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate |
| InChIKey | KKIWVYLOTHCGRV-UHFFFAOYSA-L |
| INCHI | 1S/C20H25N7O6.2Na/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);;/q;2*+1/p-2 |
| Isomeric SMILES | CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] |
| WGK Germany | 3 |
| Molecular Weight | 503.42 |
| Reaxy-Rn | 15004877 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15004877&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pteridines and derivatives |
| Subclass | Pterins and derivatives |
| Intermediate Tree Nodes | Tetrahydropteroic acids and derivatives - Tetrahydrofolic acids and derivatives |
| Direct Parent | Tetrahydrofolic acids |
| Alternative Parents | Glutamic acid and derivatives Hippuric acids N-acyl-alpha amino acids Aminobenzamides Dialkylarylamines Benzoyl derivatives Aniline and substituted anilines Phenylalkylamines Secondary alkylarylamines Aminopyrimidines and derivatives Pyrimidones Dicarboxylic acids and derivatives Heteroaromatic compounds Vinylogous amides Carboxylic acid salts Secondary carboxylic acid amides Amino acids Azacyclic compounds Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organic zwitterions Organopnictogen compounds Primary amines |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Tetrahydrofolic acid - Glutamic acid or derivatives - Hippuric acid or derivatives - Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Aminobenzamide - Aminobenzoic acid or derivatives - Benzamide - Benzoic acid or derivatives - Benzoyl - Phenylalkylamine - Aniline or substituted anilines - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Aminopyrimidine - Pyrimidone - Secondary aliphatic/aromatic amine - Dicarboxylic acid or derivatives - Monocyclic benzene moiety - Pyrimidine - Benzenoid - Vinylogous amide - Heteroaromatic compound - Carboxylic acid salt - Tertiary amine - Secondary carboxylic acid amide - Carboxamide group - Amino acid - Amino acid or derivatives - Carboxylic acid derivative - Carboxylic acid - Azacycle - Secondary amine - Organic alkali metal salt - Amine - Organic sodium salt - Organonitrogen compound - Carbonyl group - Hydrocarbon derivative - Organooxygen compound - Primary amine - Organic oxide - Organic nitrogen compound - Organopnictogen compound - Organic oxygen compound - Organic salt - Organic zwitterion - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as tetrahydrofolic acids. These are heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with at least one L-glutamic acid unit. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2509382 | Certificate of Analysis | Jul 15, 2025 | M776889 |
| G2509406 | Certificate of Analysis | Jul 15, 2025 | M776889 |
| G2509407 | Certificate of Analysis | Jul 15, 2025 | M776889 |
| G2509408 | Certificate of Analysis | Jul 15, 2025 | M776889 |
| G2509409 | Certificate of Analysis | Jul 15, 2025 | M776889 |
| Solubility | Soluble in water (25 mg/ml). |
|---|---|
| Molecular Weight | 503.400 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 7 |
| Exact Mass | 503.151 Da |
| Monoisotopic Mass | 503.151 Da |
| Topological Polar Surface Area | 204.000 Ų |
| Heavy Atom Count | 35 |
| Formal Charge | 0 |
| Complexity | 854.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 3 |
