9-Amino-6-chloro-2-methoxyacridine - Moligand™, 10 mM in DMSO , CAS No.3548-09-2

CAS: 3548-09-2 Cat. No.: A1495122 Molecular Weight: 258.7 EC Number: 636-858-3

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H + /solute antiport system.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Product Properties

• Excitation and Emision Ranges: λex 411 nm, λem 475 nm in methanol
• pKa: pKₐ: 8.69 (Predicted)
• Ki Data: Trypanothione reductase: Ki= 7 μM (Trypanosoma cruzi)

Names and Identifiers

• Isomeric SMILES: COC1=CC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)N
• WGK Germany: 3
• RTECS: AR7330000
• Molecular Weight: 258.7
• Reaxy-Rn: 226315
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=226315&ln=

Chemical and Physical Properties

• Refractive Index: n20D1.73 (Predicted)

References

1. Xinda Li, Xiaoyi Luo, Bin Wang, Lei Fu, Xi Chen, Yu Lu.  (2025)  Sudapyridine (WX-081) inhibits Mycobacterium tuberculosis by targeting ATP synthase and upregulating host innate immunity.  mSphere,      [PMID:40396746] [10.1128/msphere.00149-25]