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· · COA & SDS available for every product · Same-day shipping on in-stock items A 804598 - Moligand™, ≥98% , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
Potent, competitive P2X7receptor antagonist (IC50values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7receptors respectively). Selective for P2X7receptors (IC50> 5-10μM for a wide array of cell surface receptors and ion channels). Binds with high
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Antagonist of P2X7
Names and Identifiers Pubchem Sid 504771149 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504771149 Canonical Smiles CC(C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3 IUPAC Name 1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine InChIKey PQYCRDPLPKGSME-AWEZNQCLSA-N INCHI 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1 Isomeric SMILES C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3 Molecular Weight 315.37 Reaxy-Rn 31636225 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31636225&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data 3D Structure Associated Targets(Human) Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 31.54, Max Conc. mM: 100 Molecular Weight 315.400 g/mol XLogP3 4.000 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 5 Exact Mass 315.148 Da Monoisotopic Mass 315.148 Da Topological Polar Surface Area 73.100 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 473.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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Reconstitution Calculator Reviews Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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