AEG 3482 - ≥99%(HPLC) , CAS No.63735-71-7

CAS: 63735-71-7 Cat. No.: A287091 Molecular Weight: 280.33
AVAILABLE TO ORDER
GRADE & PURITY ≥99%(HPLC)
Synonyms
6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide | NCGC00167812-02 | Q27195229 | NCGC00167812-06 | Oprea1_698164 | SCHEMBL2540289 | 7EZF1A283N | HMS3677N15 | BCP01890 | CCG-221955 | NCGC00167812-01 | HY-107599 | AEG3482 | AEG-3482 | HMS1538B12 | Imi
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
A287091-5mg
3

$52.90

$79.90
Save $27.00 (33.79%)
10mg
A287091-10mg
3

$94.90

$142.90
Save $48.00 (33.59%)
25mg
A287091-25mg
3

$145.90

$218.90
Save $73.00 (33.35%)
50mg
A287091-50mg
2

$247.90

$371.90
Save $124.00 (33.34%)
100mg
A287091-100mg
2

$446.90

$670.90
Save $224.00 (33.39%)
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Why this grade

≥99%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
6-phenylimidazo[2, 1-b][1, 3, 4]thiadiazole-2-sulfonamide | NCGC00167812-02 | Q27195229 | NCGC00167812-06 | Oprea1_698164 | SCHEMBL2540289 | 7EZF1A283N | HMS3677N15 | BCP01890 | CCG-221955 | NCGC00167812-01 | HY-107599 | AEG3482 | AEG-3482 | HMS1538B12 | Imi
Specifications & Purity
≥99%(HPLC)
Biochemical and Physiological Mechanisms
Inhibitor of c-jun N-terminal kinase (JNK) signaling. Binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Antiapoptotic; inhibits NGF withdrawal-induced death in SCG neuro
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Purity
≥99%(HPLC)
Names and Identifiers
Canonical SmilesC1=CC=C(C=C1)C2=CN3C(=N2)SC(=N3)S(=O)(=O)N
IUPAC Name6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide
InChIKeyMQUYTXDAVCOCMX-UHFFFAOYSA-N
INCHI1S/C10H8N4O2S2/c11-18(15,16)10-13-14-6-8(12-9(14)17-10)7-4-2-1-3-5-7/h1-6H,(H2,11,15,16)
Isomeric SMILES C1=CC=C(C=C1)C2=CN3C(=N2)SC(=N3)S(=O)(=O)N
WGK Germany 3
Molecular Weight 280.33
Reaxy-Rn 1007641
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1007641&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassAzoles
SubclassImidazoles
Intermediate Tree Nodes Substituted imidazoles
Direct ParentPhenylimidazoles
Alternative Parents Thiadiazole sulfonamides  Organosulfonamides  N-substituted imidazoles  Benzene and substituted derivatives  Heteroaromatic compounds  Aminosulfonyl compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 5-phenylimidazole - 4-phenylimidazole - 1,3,4-thiadiazole-2-sulfonamide - Monocyclic benzene moiety - N-substituted imidazole - Organosulfonic acid amide - Benzenoid - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Heteroaromatic compound - Sulfonyl - Thiadiazole - Aminosulfonyl compound - Azacycle - Organic oxide - Organopnictogen compound - Organic oxygen compound - Hydrocarbon derivative - Organonitrogen compound - Organosulfur compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
A2306437Certificate of AnalysisOct 14, 2025 A287091
A2306435Certificate of AnalysisOct 14, 2025 A287091
A2306431Certificate of AnalysisOct 13, 2025 A287091
A2306433Certificate of AnalysisOct 13, 2025 A287091
A2306434Certificate of AnalysisOct 13, 2025 A287091
C2528278Certificate of AnalysisOct 24, 2022 A287091
Chemical and Physical Properties
SolubilitySolvent:DMSO, Max Conc. mg/mL: 28.03, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 1.4, Max Conc. mM: 5
Molecular Weight280.300 g/mol
XLogP31.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass280.009 Da
Monoisotopic Mass280.009 Da
Topological Polar Surface Area127.000 Ų
Heavy Atom Count18
Formal Charge0
Complexity405.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
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