Anagyrine - ≥97% , CAS No.486-89-5

CAS: 486-89-5 Cat. No.: A647058 Molecular Weight: 244.33 EC Number: 689-182-6 PubChem CID: 442938
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
A647058-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$280.90
5mg
A647058-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$820.90
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus. Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensitizer of nAChR , and Anagyrine can directly, without metabolism, desensitize nAChR .

In Vitro

Anagyrine acts as a partial agonist in both cell lines with EC 50 values of 4.2 and 231 μM in SH-SY5Y and TE-671 cells, respectively. Anagyrine is a desensitizer of nAChR with DC 50 values of 6.9 and 139 μM in SH-SY5Y and TE-671 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Oil

Specifications

Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
Anagyrine ((-)-Anagyrine) is a quinolizidine alkaloid that has been found in Lupinus albus . Anagyrine binds to muscarinic and nicotinic acetylcholine receptors with IC 50 values of 132 and 2096 µM respectively. Anagyrine is a potent and effective desensi
Storage
Protected from light, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Purity
≥97%
Names and Identifiers
Isomeric SMILES C1CCN2C[C@@H]3C[C@@H]([C@H]2C1)CN4C3=CC=CC4=O
PubChem CID 442938
Molecular Weight 244.33

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Hepatitis B virus (7925 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
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