GRADE & PURITY 10mM in DMSO

Synonyms

Methanone, (2-methyl-1-propyl-1H-indol-3-yl)-1-naphthalenyl- | BCP09304 | Serisol Fast Yellow PL | (2R,4R)-1-[(2S)-5-carbamimidamido-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid hydrate | Exembol |

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyms

Methanone, (2-methyl-1-propyl-1H-indol-3-yl)-1-naphthalenyl- | BCP09304 | Serisol Fast Yellow PL | (2R, 4R)-1-[(2S)-5-carbamimidamido-2-(3-methyl-1, 2, 3, 4-tetrahydroquinoline-8-sulfonamido)pentanoyl]-4-methylpiperidine-2-carboxylic acid hydrate | Exembol |

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Potent competitive thrombin inhibitor ( K i = 19 nM). Anticoagulant activity. Active in vivo .

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C[C@@H]1CCN([C@H](C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C.O
• WGK Germany: 3
• RTECS: TM6126610
• PubChem CID: 92721
• Molecular Weight: 508.64

Chemical and Physical Properties

• Sensitivity: Light Sensitive,Heat Sensitive
• Specific Rotation[α]: 165° (C=0.8,MeOH)
• Melt Point(°C): 180 °C(dec.)

References

1. Juan Wang, Mengmeng Song, Chengguo Hu, Kangbing Wu.  (2018)  Portable, Self-Powered, and Light-Addressable Photoelectrochemical Sensing Platforms Using pH Meter Readouts for High-Throughput Screening of Thrombin Inhibitor Drugs.  ANALYTICAL CHEMISTRY,      [PMID:29998727] [10.1021/acs.analchem.8b01979]