Bay 55-9837 TFA , Agonist of PAC 1 receptor;Agonist of VPAC 1 receptor;Agonist of VPAC 2 receptor, CAS No.463930-25-8, Agonist of PAC 1 receptor;Agonist of VPAC 1 receptor;Agonist of VPAC 2 receptor

CAS: 463930-25-8 Cat. No.: B288002 Molecular Weight: 3742.29（free basis） PubChem CID: 72941824

GRADE & PURITY Moligand™, ≥98%

Overview

Bay 55-9837 TFA is a potent and highly selective agonist of VPAC2. Bay 55-9837 TFA may be a useful therapy for the research of type 2 diabetes.

Specifications

Product Name

Bay 55-9837 TFA , Agonist of PAC 1 receptor;Agonist of VPAC 1 receptor;Agonist of VPAC 2 receptor, CAS No.463930-25-8

Synonyms

UNII-SQD60KZ8RJ | His-ser-asp-ala-val-phe-thr-asp-asn-tyr-thr-arg-leu-arg-lys-gln-val-ala-ala-lys-lys-tyr-leu-gln-ser-ile-lys-asp-lys-arg-tyr-NH2 | BAY-55-9837 | AKOS024457254 | SQD60KZ8RJ | PD079349

Grade

Moligand™

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

Selective VPAC2receptor agonist (EC50values are 0.4, 100 and >1000 nM for VPAC2, VPAC1and PAC1, respectively in a cAMP accumulation assay; IC50values are 60, 8700 and >10000 nM for VPAC2, VPAC1and PAC1, respectively in a competition binding assay). Stimul

Sequence

HSDAVFTDNYTRLRKQVAAKKYLQSIKNKRY(Modifications: Tyr-31 = C-terminal amide)

Action Type

AGONIST

Mechanism of action

Agonist of PAC 1 receptor;Agonist of VPAC 1 receptor;Agonist of VPAC 2 receptor

CAS

463930-25-8

Molecule Type

Small molecule

Storage and Shipping

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Associated Targets(Human)

VIPR2 Tchem Vasoactive intestinal polypeptide receptor 2 (0 Activities)

Discover Target: VIPR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VIPR1 Tchem Vasoactive intestinal polypeptide receptor 1 (0 Activities)

Discover Target: VIPR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADCYAP1R1 Tchem Pituitary adenylate cyclase-activating polypeptide type I receptor (0 Activities)

Discover Target: ADCYAP1R1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Genetic information

• Alternate Names: UNII-SQD60KZ8RJ | His-ser-asp-ala-val-phe-thr-asp-asn-tyr-thr-arg-leu-arg-lys-gln-val-ala-ala-lys-lys-tyr-leu-gln-ser-ile-lys-asp-lys-arg-tyr-NH2 | BAY-55-9837 | AKOS024457254 | SQD60KZ8RJ | PD079349
• Reference:
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