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· · COA & SDS available for every product · Same-day shipping on in-stock items Buspirone hydrochloride - 10mM in DMSO , Serotonin 1a (5-HT1a) receptor partial agonist, CAS No.33386-08-2, Serotonin 1a (5-HT1a) receptor partial agonist
GRADE & PURITY 10mM in DMSO
Synonyms
SW155073-5 | APC-6002 | BUSPIRONE HYDROCHLORIDE [ORANGE BOOK] | Buspirone hydrochloride [USAN:USP] | Establix | MLS001076085 | NCGC00093692-02 | Tutran | 207LT9J9OC | Buspirone (hydrochloride) | BUSPIRONE HYDROCHLORIDE (USP MONOGRAPH) | Buspirone hydrochl
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Product Describtion:
Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research.
Specifications Synonyms
SW155073-5 | APC-6002 | BUSPIRONE HYDROCHLORIDE [ORANGE BOOK] | Buspirone hydrochloride [USAN:USP] | Establix | MLS001076085 | NCGC00093692-02 | Tutran | 207LT9J9OC | Buspirone (hydrochloride) | BUSPIRONE HYDROCHLORIDE (USP MONOGRAPH) | Buspirone hydrochl
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Classic 5-HT1Apartial agonist with relatively high affinity (Ki= 9.3 - 29.5 nM). A clinically effective anxiolytic.
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
PARTIAL AGONIST
Mechanism of action
Serotonin 1a (5-HT1a) receptor partial agonist
Names and Identifiers Canonical Smiles C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl IUPAC Name 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride InChIKey RICLFGYGYQXUFH-UHFFFAOYSA-N INCHI 1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H Isomeric SMILES C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl WGK Germany 3 Molecular Weight 421.964 Reaxy-Rn 5369604 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5369604&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazinanes Subclass Piperazines Intermediate Tree Nodes Not available Direct Parent N-arylpiperazines Alternative Parents Azaspirodecane derivatives Piperidinediones Dialkylarylamines Aminopyrimidines and derivatives Delta lactams N-alkylpiperazines N-substituted carboxylic acid imides Dicarboximides Heteroaromatic compounds Amino acids and derivatives Trialkylamines Azacyclic compounds Hydrochlorides Organic oxides Carbonyl compounds Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Azaspirodecanedione - N-arylpiperazine - Azaspirodecane - Piperidinedione - Dialkylarylamine - Aminopyrimidine - Delta-lactam - Piperidinone - N-alkylpiperazine - Carboxylic acid imide, n-substituted - Piperidine - Pyrimidine - Carboxylic acid imide - Dicarboximide - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Amino acid or derivatives - Lactam - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Amine - Organonitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Hydrochloride - Organooxygen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as n-arylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an aryl group. External Descriptors hydrochloride Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 42.2, Max Conc. mM: 100; Solvent:water, Max Conc. mg/mL: 42.2, Max Conc. mM: 100 Sensitivity Moisture sensitive. Molecular Weight 422.000 g/mol XLogP3 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 6 Exact Mass 421.224 Da Monoisotopic Mass 421.224 Da Topological Polar Surface Area 69.600 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 529.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
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