≥90% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Calpain Inhibitor XII is a cell-permeable, potent, selective, reversible, and active-site-directed inhibitor of calpain-1 (K|i|= 19 nM). Calpain Inhibitor XII has been shown to inhibit calpain-2 (K|i|= 120 nM) and human cathepsin B (K|i|= 750 nM) only at higher concentrations. Calpain Inhibitor XII has been reported to induce neutrophile polarization and chemokinesis.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | Leucine and derivatives |
| Alternative Parents | Alpha amino acid amides Benzyloxycarbonyls Pyridines and derivatives N-acyl amines Heteroaromatic compounds Carbamate esters Secondary carboxylic acid amides Ketones Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Leucine or derivatives - Alpha-amino acid amide - Benzyloxycarbonyl - Monocyclic benzene moiety - Fatty amide - N-acyl-amine - Pyridine - Fatty acyl - Benzenoid - Heteroaromatic compound - Carbamic acid ester - Secondary carboxylic acid amide - Ketone - Carboxamide group - Azacycle - Organoheterocyclic compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as leucine and derivatives. These are compounds containing leucine or a derivative thereof resulting from reaction of leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2512239 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512246 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512260 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512262 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512263 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512264 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512265 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512266 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512288 | Certificate of Analysis | Nov 06, 2024 | C341237 |
| F2512289 | Certificate of Analysis | Nov 06, 2024 | C341237 |
