≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Cefcapene pivoxil hydrochloride, an antibiotic , is an orally active and potent 3rd-generation cephalosporin with a wide spectrum of anti-bacterial activity Cefcapene pivoxil hydrochloride has the potential for the palmoplantar pustulosis (PPP) treatment .
In Vivo
Cefcapene pivoxil hydrochloride (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×10 9 CFU)Dosage: 100 mg/kg Administration: Oral administration; 100mg/kg; 4 days Result: Was against H. influenzae colonization in mouse lung.
Form:Solid
IC50& Target:β-lactam
| Canonical Smiles | CCC=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)OCOC(=O)C(C)(C)C.Cl |
|---|---|
| IUPAC Name | 2,2-dimethylpropanoyloxymethyl (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;hydrochloride |
| InChIKey | ALPFRUJYOAKQQR-CQZSJNSUSA-N |
| INCHI | 1S/C23H29N5O8S2.ClH/c1-5-6-12(13-9-38-21(24)26-13)16(29)27-14-17(30)28-15(11(7-34-22(25)33)8-37-18(14)28)19(31)35-10-36-20(32)23(2,3)4;/h6,9,14,18H,5,7-8,10H2,1-4H3,(H2,24,26)(H2,25,33)(H,27,29);1H/b12-6-;/t14-,18-;/m1./s1 |
| Isomeric SMILES | CC/C=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)OCOC(=O)C(C)(C)C.Cl |
| PubChem CID | 6918126 |
| Molecular Weight | 604.1 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Lactams |
| Subclass | Beta lactams |
| Intermediate Tree Nodes | Cephems - Cephalosporins |
| Direct Parent | Cephalosporin 3'-carbamates |
| Alternative Parents | N-acyl-alpha amino acids and derivatives 2,4-disubstituted thiazoles Acylals 1,3-thiazines 2-amino-1,3-thiazoles Dicarboxylic acids and derivatives N-acyl amines Tertiary carboxylic acid amides Carbamate esters Enoate esters Heteroaromatic compounds Secondary carboxylic acid amides Azetidines Organic carbonic acids and derivatives Dialkylthioethers Thiohemiaminal derivatives Azacyclic compounds Acetals Carbonyl compounds Organic oxides Organopnictogen compounds Primary amines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Cephalosporin 3'-carbamate - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - 2,4-disubstituted 1,3-thiazole - Acylal - Meta-thiazine - Dicarboxylic acid or derivatives - N-acyl-amine - 1,3-thiazol-2-amine - Azole - Heteroaromatic compound - Tertiary carboxylic acid amide - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Carbamic acid ester - Thiazole - Amino acid or derivatives - Azetidine - Carboxamide group - Carboxylic acid ester - Carbonic acid derivative - Secondary carboxylic acid amide - Thioether - Hemithioaminal - Dialkylthioether - Azacycle - Acetal - Carboxylic acid derivative - Organonitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Organooxygen compound - Primary amine - Organic nitrogen compound - Hydrochloride - Amine - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as cephalosporin 3'-carbamates. These are cephalosporins that are substituted at the 3'-position by a carbamate group. |
| External Descriptors | Not available |
| Solubility | DMSO : 125 mg/mL (206.92 mM; Need ultrasonic) H2O : <0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble) |
|---|---|
| Melt Point(°C) | >191° C (dec.) |
| Molecular Weight | 604.100 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 12 |
| Rotatable Bond Count | 13 |
| Exact Mass | 603.122 Da |
| Monoisotopic Mass | 603.122 Da |
| Topological Polar Surface Area | 247.000 Ų |
| Heavy Atom Count | 39 |
| Formal Charge | 0 |
| Complexity | 1060.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 2 |
