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· · COA & SDS available for every product · Same-day shipping on in-stock items CP-671305 - ≥98% , CAS No.445295-04-5
Synonyms
NCGC00248048-01 | 9LH034R9R9 | CAS-445295-04-5 | CCG-15109 | CNIGFESSDPOCKS-CYBMUJFWSA-N | SCHEMBL2154519 | AKOS040758617 | DTXCID4027282 | UNII-9LH034R9R9 | CP671305 | CP-671305 | (R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophe
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Information
CP-671305 is a potent, selective and orally active inhibitor ofphosphodiesterase-4-D (PDE4-D)with IC50 of 3 nM.
Targets
PDE4-D (Cell-free assay) 3 nM
Specifications Synonyms
NCGC00248048-01 | 9LH034R9R9 | CAS-445295-04-5 | CCG-15109 | CNIGFESSDPOCKS-CYBMUJFWSA-N | SCHEMBL2154519 | AKOS040758617 | DTXCID4027282 | UNII-9LH034R9R9 | CP671305 | CP-671305 | (R)-2-(4-((2-(benzo[d][1, 3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophe
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
CP-671305 is a potent, selective and orally active inhibitor of phosphodiesterase-4-D (PDE4-D) with IC50 of 3 nM.
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties ALogP 3.493 hba_count 7 HBD Count 1 Rotatable Bond 8
Names and Identifiers Pubchem Sid 504765151 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504765151 Canonical Smiles CC(C(=O)O)OC1=CC(=C(C=C1)CNC(=O)C2=C(N=CC=C2)OC3=CC4=C(C=C3)OCO4)F IUPAC Name (2R)-2-[4-[[[2-(1,3-benzodioxol-5-yloxy)pyridine-3-carbonyl]amino]methyl]-3-fluorophenoxy]propanoic acid InChIKey CNIGFESSDPOCKS-CYBMUJFWSA-N INCHI 1S/C23H19FN2O7/c1-13(23(28)29)32-15-5-4-14(18(24)9-15)11-26-21(27)17-3-2-8-25-22(17)33-16-6-7-19-20(10-16)31-12-30-19/h2-10,13H,11-12H2,1H3,(H,26,27)(H,28,29)/t13-/m1/s1 Isomeric SMILES C[C@H](C(=O)O)OC1=CC(=C(C=C1)CNC(=O)C2=C(N=CC=C2)OC3=CC4=C(C=C3)OCO4)F Molecular Weight 454.4 Reaxy-Rn 14109925 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14109925&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass 2-phenoxypropionic acids Intermediate Tree Nodes Not available Direct Parent 2-phenoxypropionic acids Alternative Parents Phenoxyacetic acid derivatives Diarylethers Nicotinamides Benzodioxoles Phenoxy compounds Phenol ethers Alkyl aryl ethers Fluorobenzenes Aryl fluorides Heteroaromatic compounds Secondary carboxylic acid amides Oxacyclic compounds Acetals Azacyclic compounds Monocarboxylic acids and derivatives Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Organic oxides Organofluorides Organonitrogen compounds Organopnictogen compounds Molecular Framework Aromatic heteropolycyclic compounds Substituents 2-phenoxypropionic acid - Phenoxyacetate - Diaryl ether - Nicotinamide - Benzodioxole - Pyridine carboxylic acid or derivatives - Phenoxy compound - Phenol ether - Alkyl aryl ether - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Pyridine - Heteroaromatic compound - Carboxamide group - Secondary carboxylic acid amide - Acetal - Carboxylic acid derivative - Carboxylic acid - Oxacycle - Ether - Azacycle - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Carbonyl group - Hydrocarbon derivative - Organooxygen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as 2-phenoxypropionic acids. These are aromatic compounds hat contain a phenol ether attached to the C2-atom of a phenylpropionic acid. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solubility (25°C) In vitro DMSO: 91 mg/mL (200.26 mM); Ethanol: 20 mg/mL (44.01 mM); Water: Insoluble; DMSO(mg / mL) Max Solubility 91 DMSO(mM) Max Solubility 200.264084507042 Water(mg / mL) Max Solubility ＜1 Molecular Weight 454.400 g/mol XLogP3 3.400 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 9 Rotatable Bond Count 8 Exact Mass 454.118 Da Monoisotopic Mass 454.118 Da Topological Polar Surface Area 116.000 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 683.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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