≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Ethyl 3,4-Dihydroxybenzoate is an antioxidant compound. It also exhibits anti-inflammatory, anti-parasitic, antibacterial, anti-metastatic, and anticancer activities. Protocatechuic acid inhibits TNF-induced expression and release of adhesion molecules and pro-inflammatory cytokines as well as ADP-induced expression of platelet P-selectin. This compound increases quinone reductase activity and acts as a radical scavenger. Protocatechuic acid ethyl ester inhibits RhoB activation, decreasing expression of matrix metalloproteinase 2 (MMP2) and inactivating NF-κB and also inhibits human topoisomerase II. An antioxidant
Phenolic compound. Substrate analog and competitive inhibitor of prolyl 4-hydroxylase. Protocatechuic acid ( Asc 2937 ) derivative. Shows cardioprotective, neuroprotective and antimicrobial effects in vivo.
Storage
Room temperature
Shipped In
Normal
Action Type
ACTIVATOR
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as p-hydroxybenzoic acid alkyl esters. These are aromatic compounds containing a benzoic acid, which is esterified with an alkyl group and para-substituted with a hydroxyl group.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
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