FD223 - ≥98% , CAS No.2050524-24-6

CAS: 2050524-24-6 Cat. No.: F1420610 Molecular Weight: 385.83

GRADE & PURITY ≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

FD223 is a potent and selective phosphoinositide 3-kinase delta ( PI3Kδ ) inhibitor. FD223 displays high potency ( IC 50 =1 nM) and good selectivity over other isoforms (IC 50 s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML.

Specifications

Specifications & Purity

≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

ACTIVATOR

Purity

≥98%

Names and Identifiers

• Molecular Weight: 385.83