Galloflavin Potassium Dihydrate - Moligand™, ≥95% , CAS No.1780260-20-9

CAS: 1780260-20-9 Cat. No.: G287467 Molecular Weight: 352.29

GRADE & PURITY Moligand™, ≥95%

Synonyms

3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione potassium salt

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Galloflavin potassium is a novel lactate dehydrogenase inhibitor that can be used for the research of cancer. Galloflavin inhibits aerobic glycolysis in PLC/PRF/5 cells and triggers cell death via apoptosis.

Specifications

Synonyms

3, 8, 9, 10-Tetrahydroxypyrano[3, 2-c][2]benzopyran-2, 6-dione potassium salt

Specifications & Purity

Moligand™, ≥95%

Biochemical and Physiological Mechanisms

Inhibitor of human lactate dehydrogenase (LDH) (Kivalues are 5.46 and 15.1μM for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability v

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C1=C2C(=C3C(=CC(=C(O3)O)[O-])OC2=O)C(=C(C1=O)O)O.[K+]
• IUPAC Name: potassium;2,9,10-trihydroxy-6,8-dioxopyrano[3,2-c]isochromen-3-olate
• InChIKey: ZXTYKQDMPYEPEX-UHFFFAOYSA-M
• INCHI: 1S/C12H6O8.K/c13-4-1-3-7(9(16)8(4)15)10-6(19-11(3)17)2-5(14)12(18)20-10;/h1-2,14-16,18H;/q;+1/p-1
• Alternate CAS: 568-80-9
• Molecular Weight: 352.29

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 1.58, Max Conc. mM: 5