Histamine diphosphate monohydrate - 10mM in Water , Histamine H1 receptor agonist, CAS No.51-74-1, Histamine H1 receptor agonist

CAS: 51-74-1 Cat. No.: H424438 Molecular Weight: 325.15 Beilstein Registry Number: 3744619 EC Number: 200-118-4

GRADE & PURITY 10mM in Water

Synonyms

Histamine phosphate [USP] | MFCD00064316 | Histamine Phosphate,(S) | Histamine acid phosphate | AC-24100 | DTXSID7058759 | HY-A0129 | Histamine diphosphate, 98% | Histaminephosphate | QWB37T4WZZ | Histamine phosphate (USP) | UNII-QWB37T4WZZ | 1H-Imidazole

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Histamine bisphosphate monohydrate is a potent agonist of histamine receptors.
A potent histamine receptor agonist

Specifications

Synonyms

Histamine phosphate [USP] | MFCD00064316 | Histamine Phosphate, (S) | Histamine acid phosphate | AC-24100 | DTXSID7058759 | HY-A0129 | Histamine diphosphate, 98% | Histaminephosphate | QWB37T4WZZ | Histamine phosphate (USP) | UNII-QWB37T4WZZ | 1H-Imidazole

Specifications & Purity

10mM in Water

Biochemical and Physiological Mechanisms

Phosphate salt of Histamine . Acts as a neurotransmitter in the nervous system and as a local mediator in the gut, skin, and immune system.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

AGONIST

Mechanism of action

Histamine H1 receptor agonist

Names and Identifiers

• Canonical Smiles: C1=C(NC=N1)CCN.OP(=O)(O)O.OP(=O)(O)O
• IUPAC Name: 2-(1H-imidazol-5-yl)ethanamine;phosphoric acid
• InChIKey: ZHIBQGJKHVBLJJ-UHFFFAOYSA-N
• INCHI: 1S/C5H9N3.2H3O4P/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4)
• Isomeric SMILES: C1=C(NC=N1)CCN.OP(=O)(O)O.OP(=O)(O)O
• WGK Germany: 3
• RTECS: NI5425000
• Alternate CAS: 23297-93-0
• Molecular Weight: 325.15
• Beilstein: 3744619
• Reaxy-Rn: 6250304
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6250304&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Primary amines
          • Level6 2-arylethylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Primary amines
• Direct Parent: 2-arylethylamines
• Alternative Parents: Aralkylamines Organic phosphoric acids and derivatives Imidazoles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2-arylethylamine - Aralkylamine - Organic phosphoric acid derivative - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary aliphatic amine - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as 2-arylethylamines. These are primary amines that have the general formula RCCNH2, where R is an organic group.
• External Descriptors: phosphate salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Heat & Moisture sensitive
• Melt Point(°C): 126-132°C
• Molecular Weight: 307.140 g/mol
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 2
• Exact Mass: 307.033 Da
• Monoisotopic Mass: 307.033 Da
• Topological Polar Surface Area: 210.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 114.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3