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· · COA & SDS available for every product · Same-day shipping on in-stock items Hydroxyzine dihydrochloride - 10mM in DMSO , Histamine H1 receptor antagonist, CAS No.2192-20-3, Histamine H1 receptor antagonist
GRADE & PURITY 10mM in DMSO
Synonyms
Hydroxyzine dihydrochloride|2192-20-3|Hydroxyzine hydrochloride|Hydroxyzine 2HCl|2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride|Orgatrax|Alamon|Atarax|Hydroxyzine Hcl|Durrax|Atranine A|Hydroxyzine (dihydrochloride)|A
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist
Specifications Synonyms
Hydroxyzine dihydrochloride | 2192-20-3 | Hydroxyzine hydrochloride | Hydroxyzine 2HCl | 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride | Orgatrax | Alamon | Atarax | Hydroxyzine Hcl | Durrax | Atranine A | Hydroxyzine (dihydrochloride) | A
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
The biochemical mechanism was changed to H1 receptor antagonist. Shows anxiolytic effects in vivo.
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Histamine H1 receptor antagonist
Names and Identifiers Canonical Smiles C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl IUPAC Name 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride InChIKey ANOMHKZSQFYSBR-UHFFFAOYSA-N INCHI 1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H Isomeric SMILES C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl WGK Germany 3 RTECS KK2280000 PubChem CID 91513 Molecular Weight 447.83
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Diphenylmethanes Intermediate Tree Nodes Not available Direct Parent Diphenylmethanes Alternative Parents N-alkylpiperazines Chlorobenzenes Aralkylamines Aryl chlorides Trialkylamines Dialkyl ethers Azacyclic compounds Primary alcohols Organopnictogen compounds Organochlorides Hydrochlorides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Diphenylmethane - Chlorobenzene - Halobenzene - N-alkylpiperazine - Aralkylamine - Aryl chloride - Aryl halide - 1,4-diazinane - Piperazine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Organoheterocyclic compound - Dialkyl ether - Ether - Hydrochloride - Organochloride - Organohalogen compound - Organopnictogen compound - Organonitrogen compound - Organic oxygen compound - Organooxygen compound - Organic nitrogen compound - Amine - Hydrocarbon derivative - Alcohol - Primary alcohol - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups. External Descriptors hydrochloride Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 447.800 g/mol XLogP3 Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 8 Exact Mass 446.129 Da Monoisotopic Mass 446.129 Da Topological Polar Surface Area 35.900 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 376.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 1 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 3
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