Inosine 5′-triphosphate trisodium salt - 10mM in Water , CAS No.35908-31-7

CAS: 35908-31-7 Cat. No.: I423617 Molecular Weight: 574.11 EC Number: 680-179-5 PubChem CID: 135742691

GRADE & PURITY 10mM in Water

Synonyms

35908-31-7|Inosine-5'-triphosphate trisodium salt|Inosine 5'-triphosphate trisodium salt|Inosine 5' Triphosphate Trisodium Salt|ITP|trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hy

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.

Specifications

Synonyms

35908-31-7 | Inosine-5'-triphosphate trisodium salt | Inosine 5'-triphosphate trisodium salt | Inosine 5' Triphosphate Trisodium Salt | ITP | trisodium;[[[(2R, 3S, 4R, 5R)-3, 4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hy

Specifications & Purity

10mM in Water

Biochemical and Physiological Mechanisms

Inosine 5′-triphosphate (ITP) has the ability to support the initiation of effector system. It can prevent guanosine 5′-triphosphate (GTP) hydrolysis, that is catalysed by transducin (TD). ITP can proficiently induce secretion in permeabilized cells than

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
• InChIKey: QRGLCGLOQVQVCS-MSQVLRTGSA-K
• INCHI: 1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
• Isomeric SMILES: C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
• WGK Germany: 1
• PubChem CID: 135742691
• Molecular Weight: 574.11

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleotides
      • Subclass Purine ribonucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine ribonucleoside triphosphates
• Alternative Parents: Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Hypoxanthines Monosaccharide phosphates Pyrimidones Alkyl phosphates N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Organonitrogen compounds Hydrocarbon derivatives Organic zwitterions Organic oxides Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside triphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Monosaccharide phosphate - Imidazopyrimidine - Purine - Pyrimidone - Alkyl phosphate - Monosaccharide - Pyrimidine - N-substituted imidazole - Phosphoric acid ester - Organic phosphoric acid derivative - Azole - Vinylogous amide - Imidazole - Heteroaromatic compound - Oxolane - 1,2-diol - Secondary alcohol - Oxacycle - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Hydrocarbon derivative - Alcohol - Organic zwitterion - Organic salt - Organic oxygen compound - Organic nitrogen compound - Organic sodium salt - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine ribonucleoside triphosphates. These are purine ribobucleotides with a triphosphate group linked to the ribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Sensitivity: Heat sensitive;Moisture sensitive
• Molecular Weight: 574.110 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 8
• Exact Mass: 573.926 Da
• Monoisotopic Mass: 573.926 Da
• Topological Polar Surface Area: 277.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 862.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

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