≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488182058 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488182058 |
| Canonical Smiles | C1=CN=CC=C1C(=O)N |
| IUPAC Name | pyridine-4-carboxamide |
| InChIKey | VFQXVTODMYMSMJ-UHFFFAOYSA-N |
| INCHI | 1S/C6H6N2O/c7-6(9)5-1-3-8-4-2-5/h1-4H,(H2,7,9) |
| Isomeric SMILES | C1=CN=CC=C1C(=O)N |
| WGK Germany | 3 |
| RTECS | NR9500000 |
| Molecular Weight | 122.12 |
| Beilstein | 2173 |
| Reaxy-Rn | 2173 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2173&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Pyridinecarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyridinecarboxamides |
| Alternative Parents | Heteroaromatic compounds Primary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Pyridinecarboxamide - Heteroaromatic compound - Primary carboxylic acid amide - Carboxamide group - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as pyridinecarboxamides. These are compounds containing a pyridine ring bearing a carboxamide. |
| External Descriptors | pyridinecarboxamide |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 G2227915 | Certificate of Analysis | May 19, 2026 | I106833 |
| G2227919 | Certificate of Analysis | May 19, 2026 | I106833 |
| G2227921 | Certificate of Analysis | May 19, 2026 | I106833 |
| H2106080 | Certificate of Analysis | May 12, 2025 | I106833 |
| H2106081 | Certificate of Analysis | May 12, 2025 | I106833 |
| H2106083 | Certificate of Analysis | May 12, 2025 | I106833 |
| J2514523 | Certificate of Analysis | Jun 13, 2024 | I106833 |
| J2514514 | Certificate of Analysis | Jun 13, 2024 | I106833 |
| I2426224 | Certificate of Analysis | Jun 13, 2024 | I106833 |
| I2426156 | Certificate of Analysis | Jun 13, 2024 | I106833 |
| G1903058 | Certificate of Analysis | Apr 17, 2023 | I106833 |
| L2208079 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208080 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208081 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208082 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208083 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208499 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208633 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| L2208634 | Certificate of Analysis | Sep 12, 2022 | I106833 |
| G2227920 | Certificate of Analysis | Jul 07, 2022 | I106833 |
| G2227918 | Certificate of Analysis | Jul 07, 2022 | I106833 |
| Solubility | Soluble in dioxane (10 mg/ml), methanol, water (191.7 mg/ml at 37 °C), ethanol, and DMSO. |
|---|---|
| Melt Point(°C) | 155-158°C |
| Molecular Weight | 122.120 g/mol |
| XLogP3 | -0.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 122.048 Da |
| Monoisotopic Mass | 122.048 Da |
| Topological Polar Surface Area | 56.000 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 108.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yangyang Sun, Zhuzhu Tang, Yanjun Li, Yongkang Song, Hualei Wang, Dongzhi Wei, Shengli Yang. (2023) Identification and evolution of non-traditional nitrilase from Spirosoma linguale DSM 74 with high hydration activity. BIOORGANIC CHEMISTRY, [PMID:38185008] [10.1016/j.bioorg.2023.107055] |
| 2. Bingqing Zhu, Mengyuan Xia, Zhenfeng Ding, Xiaoyi Rong, Xuefeng Mei. (2023) Enhancing physical and chemical stability of hygroscopic hydroxytyrosol by cocrystal formation. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:37793465] [10.1016/j.ijpharm.2023.123470] |
| 3. Junling Guo, Zhongyi Cheng, Lukasz Peplowski, Zhemin Zhou. (2023) Highly efficient biosynthesis of isonicotinamide through a substrate access tunnel engineered nitrile hydratase from Carbonactinospora thermoautotrophicus. NEW JOURNAL OF CHEMISTRY, 47 (28): (13279-13285). [PMID:] [10.1039/D3NJ00331K] |
| 4. Zhiyong Zheng, Yuehua Deng, Weining Xie, Sirui Chen, Xiaoxiao Liang, Shiyuan Liu, Yanbin Jiang, Huaiyu Yang. (2023) Co-Former Screening Method for Multicomponent Crystals Based on Partial Least Squares Regression: A Case Study of Ciprofloxacin. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.2c01414] |
| 5. Chun-Yan Zhang, Wei-Yi Zhang, Guo-Ying Chen, Tong-Qing Chai, Hao Zhang, Yi Xu, Feng-Qing Yang. (2022) Vitamin B3 as a high acid-alkali tolerant peroxidase mimic for colorimetric detection of hydrogen peroxide and glutathione. Arabian Journal of Chemistry, [PMID:] [10.1016/j.arabjc.2022.103823] |
| 6. Qiaoling Liu, Hongyu Mou, Wenjun Chen, Xinhui Zhao, Haitao Yu, Zhimin Xue, Tiancheng Mu. (2019) Highly Efficient Dissolution of Lignin by Eutectic Molecular Liquids. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, [PMID:] [10.1021/acs.iecr.9b05059] |
| 7. Zhen Li, Meiqi Li, Bo Peng, Bingqing Zhu, Jian-rong Wang, Xuefeng Mei. (2019) Improving Compliance and Decreasing Drug Accumulation of Diethylstilbestrol through Cocrystallization. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.8b01911] |
| 8. Shuzhen Ren, Mingyu Liu, Chao Hong, Guowen Li, Jiabin Sun, Jianying Wang, Lei Zhang, Yan Xie. (2018) The effects of pH, surfactant, ion concentration, coformer, and molecular arrangement on the solubility behavior of myricetin cocrystals. Acta Pharmaceutica Sinica B, [PMID:30766778] [10.1016/j.apsb.2018.09.008] |
| 9. Yanlei Kang, Jianming Gu, Xiurong Hu. (2016) Syntheses, structure characterization and dissolution of two novel cocrystals of febuxostat. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2016.10.044] |
| 10. Hongli Sun, Yiwei Wu. (2013) Field-amplified sample injection for the determination of isonicotinamide and nicotinamide in whitening cosmetics and supplemented foodstuffs by MEKC. Analytical Methods, 5 (20): (5615-5621). [PMID:] [10.1039/C3AY40914G] |
| 11. Zhanghao Wu, Yue Zhao, Changlei Wang, Tianshu Ma, Chen Chen, Yuhui Liu, Tianci Jia, Yuhang Zhai, Cong Chen, Cheng Zhang, Guogyang Cao, Zhenhai Yang, Dewei Zhao, Xiaofeng Li. (2025) Enhancing Photovoltaically Preferred Orientation in Wide-Bandgap Perovskite for Efficient All-Perovskite Tandem Solar Cells. ADVANCED MATERIALS, [PMID:39763405] [10.1002/adma.202412943] |
| 12. Guiyu Chen, Pengpeng Yang, Mengyang Cai, Keke Zhang. (2025) The Confinement Crystallization Behavior of Isonicotinamide within Functionalized Pores: Correlation between Polymorph Selection and Surface Chemistry. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.5c00983] |
