≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
JNJ-10229570 JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R). JNJ-10229570 inhibits sebaceous gland differentiation and the production of sebum-specific lipids. JNJ-10229570 inhibits the binding of 125I-NDP-α-MSH to cells expressing human MC1R and MC5R with IC50 of 270 nM and 200 nM, respectively.
| Pubchem Sid | 504765254 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765254 |
| Canonical Smiles | COC1=CC=CC=C1C2=NC(=NC3=CC=CC=C3)SN2C4=CC=CC=C4OC |
| IUPAC Name | 2,3-bis(2-methoxyphenyl)-N-phenyl-1,2,4-thiadiazol-5-imine |
| InChIKey | XTHRTBCPBWJYRO-UHFFFAOYSA-N |
| INCHI | 1S/C22H19N3O2S/c1-26-19-14-8-6-12-17(19)21-24-22(23-16-10-4-3-5-11-16)28-25(21)18-13-7-9-15-20(18)27-2/h3-15H,1-2H3 |
| Isomeric SMILES | COC1=CC=CC=C1C2=NC(=NC3=CC=CC=C3)SN2C4=CC=CC=C4OC |
| Molecular Weight | 389.5 |
| Reaxy-Rn | 14630142 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14630142&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Aniline and substituted anilines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Methoxyanilines |
| Alternative Parents | Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Thiadiazoles Heteroaromatic compounds Azacyclic compounds Organonitrogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Methoxyaniline - Phenoxy compound - Anisole - Phenol ether - Methoxybenzene - Alkyl aryl ether - Azole - Heteroaromatic compound - Thiadiazole - Ether - Azacycle - Organoheterocyclic compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organic oxygen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as methoxyanilines. These are organic compound containing an aniline group substituted at one or more positions by a methoxy group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 K2307411 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308381 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308384 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308390 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308391 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308396 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308398 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308399 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308404 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308405 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308408 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| K2308409 | Certificate of Analysis | Sep 28, 2023 | J412125 |
| Solubility | Solubility (25°C) In vitro Ethanol: mg/mL |
|---|---|
| Molecular Weight | 389.500 g/mol |
| XLogP3 | 5.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 389.12 Da |
| Monoisotopic Mass | 389.12 Da |
| Topological Polar Surface Area | 71.700 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 576.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
