GRADE & PURITY 10mM in DMSO

Synonyms

1188890-41-6 | s7423 | KN 93 phosphate | KN-93 phosphate (water soluble) | F20700 | HB0360 | EX-A2086 | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate | AC-33085 | (E)-N-(2-(((3-(

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Specifications

Synonyms

1188890-41-6 | s7423 | KN 93 phosphate | KN-93 phosphate (water soluble) | F20700 | HB0360 | EX-A2086 | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate | AC-33085 | (E)-N-(2-(((3-(

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Potent, specific and cell-permeable calmodulin-dependent protein kinase (CaMK) II inhibitor (IC 50 = 370 nM). Also a potent and direct extracellular open channel voltage-gated potassium channel blocker (IC 50 = 307 nM for Kv1.5).

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
• IUPAC Name: N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide;phosphoric acid
• InChIKey: NNKJTPOXLIILMB-IPZCTEOASA-N
• INCHI: 1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+
• Isomeric SMILES: CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
• Molecular Weight: 599.03
• Reaxy-Rn: 18467446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18467446&ln=

Chemical and Physical Properties

• Sensitivity: light sensitive
• Molecular Weight: 599.000 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 11
• Exact Mass: 598.131 Da
• Monoisotopic Mass: 598.131 Da
• Topological Polar Surface Area: 156.000 Ų
• Heavy Atom Count: 39
• Formal Charge: 0
• Complexity: 763.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 2

XLogP3