10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker ( K i of 0.56-2.1 μM for NMDA receptor ; IC 50 s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects
In Vivo
Lanicemine produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects .\nLanicemine (3, 10 or 30 mg/kg; intraperitoneal) not only engages brain circuits involved in the generation of gamma- electroencephalography (EEG), but also influences these networks independent of the broader systems-level disruptions typical of ketamine . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Sprague-Dawley rats Dosage: 3, 10 or 30 mg/kg Administration: Intraperitoneal Result: Produced pronounced dose-dependent elevations in spontaneous gamma-band EEG, but only gamma changes for Ketamine were tightly coupled to increases in locomotor activity.
IC50& Target:NMDA receptor
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker ( K i of 0.56-2.1u2009μM for NMDA receptor ; IC 50 s of 4-7u2009μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ANTAGONIST
Names and Identifiers
Isomeric SMILES
C1=CC=C(C=C1)[C@H](CC2=CC=CC=N2)N.Cl.Cl
WGK Germany
3
PubChem CID
9795446
Molecular Weight
271.19
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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