Platelet-activating factor receptor (PTAFR)

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  1. Ginkgolide B, Channel blocker of 5-HT 3A;Channel blocker of 5-HT 3AB;Channel blocker of glycine receptor α1 subunit;Channel blocker of glycine receptor α2 subunit;Channel blocker of glycine receptor α3 subunit;Channel blocker of glycine receptor β subunit;Antagonist of
    CAS: 15291-77-7 EC Number: 604-876-0 Formula: C20H24O10 Molecular Weight: 424.4
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: G101969
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    IUPAC Name
    8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
    SMILES
    CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O
    InChIKey
    SQOJOAFXDQDRGF-UHFFFAOYSA-N
    InChI
    1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3
    Synonyms
    Ginkgolide B | Ginkolide B | Ginklide B | 1-Hydroxy-(1beta)-Ginkgolide A | Gingko lactone | 7-Deoxyginkgolide C | BN-...
  2. Apafant(WEB 2086), Antagonist of PAF receptor
    CAS: 105219-56-5 EC Number: 692-443-7 Formula: C22H22ClN5O2S Molecular Weight: 455.96
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Out of Stock Item #: A132597
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    IUPAC Name
    3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-morpholin-4-ylpropan-1-one
    SMILES
    CC1=NN=C2N1C3=C(C=C(S3)CCC(=O)N4CCOCC4)C(=NC2)C5=CC=CC=C5Cl
    InChIKey
    JGPJQFOROWSRRS-UHFFFAOYSA-N
    InChI
    1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3
    Synonyms
    DTXCID5028900 | HMS3268N16 | NCGC00092377-04 | PDSP1_000669 | 4-[3-[4[(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,...
  3. 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine, Agonist of PAF receptor
    CAS: 74389-68-7 Formula: C26H54NO7P Molecular Weight: 523.68
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: O130783
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    IUPAC Name
    [(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
    SMILES
    CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C
    InChIKey
    HVAUUPRFYPCOCA-AREMUKBSSA-N
    InChI
    1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
    Synonyms
    PAF C-16 | C16-02:0 PC
  4. Cilostamide, Inhibitor of phosphodiesterase 3A;Inhibitor of phosphodiesterase 3B
    CAS: 68550-75-4 Formula: C20H26N2O3 Molecular Weight: 342.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: C274669
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    IUPAC Name
    N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide
    SMILES
    CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
    InChIKey
    UIAYVIIHMORPSJ-UHFFFAOYSA-N
    InChI
    1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
    Synonyms
    BRD-K28578425-001-06-2 | EU-0100288 | Cilostamide - CAS 68550-75-4 | NCGC00015269-02 | NCGC00015269-05 | SR-010000757...
  5. Cilostamide, Inhibitor of phosphodiesterase 3A;Inhibitor of phosphodiesterase 3B
    CAS: 68550-75-4 Formula: C20H26N2O3 Molecular Weight: 342.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: C425456
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    IUPAC Name
    N-cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide
    SMILES
    CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3
    InChIKey
    UIAYVIIHMORPSJ-UHFFFAOYSA-N
    InChI
    1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23)
    Synonyms
    BRD-K28578425-001-06-2 | EU-0100288 | Cilostamide - CAS 68550-75-4 | NCGC00015269-02 | NCGC00015269-05 | SR-010000757...
  6. Ginkgolide B, Channel blocker of 5-HT 3A;Channel blocker of 5-HT 3AB;Channel blocker of glycine receptor α1 subunit;Channel blocker of glycine receptor α2 subunit;Channel blocker of glycine receptor α3 subunit;Channel blocker of glycine receptor β subunit;Antagonist of
    CAS: 15291-77-7 EC Number: 604-876-0 Formula: C20H24O10 Molecular Weight: 424.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G421813
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    IUPAC Name
    8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione
    SMILES
    CC1C(=O)OC2C1(C34C(=O)OC5C3(C2O)C6(C(C5)C(C)(C)C)C(C(=O)OC6O4)O)O
    InChIKey
    SQOJOAFXDQDRGF-UHFFFAOYSA-N
    InChI
    1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3
    Synonyms
    Ginkgolide B|15291-77-7|Ginkolide B|Gingko lactone|BN 52021|SR-01000597598|bn52021|Ginklide B|7-Deoxyginkgolide C|C20...
  7. ABT-491, Antagonist of PAF receptor
    CAS: 170499-15-7 PubChem CID: 154087
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607339
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    IUPAC Name
    4-ethynyl-3-[3-fluoro-4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-N,N-dimethylindole-1-carboxamide
    SMILES
    C#Cc1cccc2c1c(cn2C(=O)N(C)C)C(=O)c1ccc(c(c1)F)Cn1c(C)nc2c1ccnc2
    InChIKey
    GDLNHSUSOZEAOR-UHFFFAOYSA-N
    InChI
    1S/C28H22FN5O2/c1-5-18-7-6-8-25-26(18)21(16-34(25)28(36)32(3)4)27(35)19-9-10-20(22(29)13-19)15-33-17(2)31-23-14-30-12-11-24(23)33/h1,6-14,16H,15H2,2-4show more
    Synonyms
    ABT-491 free base | BDBM50062054 | GTPL1850 | 1H-Indole-1-carboxamide, 4-ethynyl-3-(3-fluoro-4-((2-methyl-1H-imidazo(...
  8. ABT-299, Antagonist of PAF receptor
    CAS: 161395-35-3 PubChem CID: 9830503
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: A607337
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    Technical Identifiers
    IUPAC Name
    [3-[(3R)-7-[1-(dimethylcarbamoyl)-6-(4-fluorophenyl)indole-3-carbonyl]-1,3-dihydropyrrolo[1,2-c][1,3]thiazol-3-yl]pyridin-1-ium-1-yl]methyl acetate chshow more
    SMILES
    CC(=O)OC[n+]1cccc(c1)[C@H]1SCc2n1ccc2C(=O)c1cn(c2c1ccc(c2)c1ccc(cc1)F)C(=O)N(C)C.[Cl-]
    InChIKey
    NKIONDJYXPXFFL-JSSVAETHSA-M
    InChI
    1S/C32H28FN4O4S.ClH/c1-20(38)41-19-35-13-4-5-23(16-35)31-36-14-12-26(29(36)18-42-31)30(39)27-17-37(32(40)34(2)3)28-15-22(8-11-25(27)28)21-6-9-24(33)10show more
    Synonyms
    742QGP819Q | UNII-742QGP819Q | Q27074121 | AKOS040747742 | [3-[(3R)-7-[1-(dimethylcarbamoyl)-6-(4-fluorophenyl)indole...
  9. CV-3988, Antagonist of PAF receptor
    CAS: 85703-73-7 PubChem CID: 107681 Formula: C28H53N2O7PS Molecular Weight: 592.77
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: C609620
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    IUPAC Name
    [2-methoxy-3-(octadecylcarbamoyloxy)propyl] 2-(1,3-thiazol-3-ium-3-yl)ethyl phosphate
    SMILES
    CCCCCCCCCCCCCCCCCCNC(=O)OCC(COP(=O)([O-])OCC[N+]1=CSC=C1)OC
    InChIKey
    NMHKTASGTFXJPL-UHFFFAOYSA-N
    InChI
    1S/C28H53N2O7PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-29-28(31)35-24-27(34-2)25-37-38(32,33)36-22-20-30-21-23-39-26-30/h21,23,26-27H,3-20,22,show more
    Synonyms
    BDBM50006048 | GLXC-26218 | AKOS040748197 | CV3988 | CV-3988 | 3-{2-[(2-Methoxy-3-octadecylcarbamoyloxy-propoxy)-phos...
  10. SDZ 64-412, Antagonist of PAF receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S613510
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    IUPAC Name
    5-[4-[2-(3,4,5-trimethoxyphenyl)ethyl]phenyl]-2,3-dihydroimidazo[2,1-a]isoquinoline
    SMILES
    COc1cc(CCc2ccc(cc2)c2cc3ccccc3c3=NCCn23)cc(c1OC)OC
    InChIKey
    FKRBSORUVOGNEK-UHFFFAOYSA-N
    InChI
    1S/C28H28N2O3/c1-31-25-16-20(17-26(32-2)27(25)33-3)9-8-19-10-12-21(13-11-19)24-18-22-6-4-5-7-23(22)28-29-14-15-30(24)28/h4-7,10-13,16-18H,8-9,14-15H2,show more
    Synonyms
    SDZ-64412
  11. SX-517, Antagonist of CXCR2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S614275
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    IUPAC Name
    [2-[[5-[(4-fluorophenyl)carbamoyl]pyridin-2-yl]sulfanylmethyl]phenyl]boronic acid
    SMILES
    Fc1ccc(cc1)NC(=O)c1ccc(nc1)SCc1ccccc1B(O)O
    InChIKey
    VZRIHFZJVIOJBE-UHFFFAOYSA-N
    InChI
    1S/C19H16BFN2O3S/c21-15-6-8-16(9-7-15)23-19(24)13-5-10-18(22-11-13)27-12-14-3-1-2-4-17(14)20(25)26/h1-11,25-26H,12H2,(H,23,24)
    Synonyms
    HY-12927 | AKOS040749589 | (2-(((5-((4-Fluorophenyl)carbamoyl)pyridin-2-yl)thio)methyl)phenyl)boronic acid | 36UH926W...
  12. [³H]PAF, Agonist of PAF receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: H614197
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    IUPAC Name
    [(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-trimethylazaniumylethyl phosphate
    SMILES
    CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-]
    InChIKey
    HVAUUPRFYPCOCA-AREMUKBSSA-N
    InChI
    1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1
    Synonyms
    [(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-trimethylazaniumylethyl phosphate | C16-PAF | 1-O-hexadecyl PAF | 2-O-acetyl-...
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