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Short transient receptor potential channel 3 (TRPC3)

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  1. GSK 2193874, Channel blocker of TRPV4
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    GSK 2193874, Channel blocker of TRPV4
    CAS: 1336960-13-4 EC Number: 808-437-6 Formula: C37H38BrF3N4O Molecular Weight: 691.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G287297
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    IUPAC Name
    7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
    SMILES
    C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7
    InChIKey
    UIVOZBSCHXCGPS-UHFFFAOYSA-N
    InChI
    1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36show more
    Synonyms
    GSK2193874 | GSK-2193874 | GTPL6465 | NCGC00370767-01 | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopr...
  2. YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
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    YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: Y276423
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
    SMILES
    CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    XPRZIORDEVHURQ-UHFFFAOYSA-N
    InChI
    1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
    Synonyms
    HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
  3. Pyr3, Channel blocker of TRPC3
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    Pyr3, Channel blocker of TRPC3
    CAS: 1160514-60-2 PubChem CID: 56964346 Formula: C16H11Cl3F3N3O3 Molecular Weight: 456.64
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P275699
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    IUPAC Name
    ethyl 1-[4-(2,3,3-trichloroprop-2-enoylamino)phenyl]-5-(trifluoromethyl)pyrazole-4-carboxylate
    SMILES
    CCOC(=O)C1=C(N(N=C1)C2=CC=C(C=C2)NC(=O)C(=C(Cl)Cl)Cl)C(F)(F)F
    InChIKey
    RZHGONNSASQOAY-UHFFFAOYSA-N
    InChI
    1S/C16H11Cl3F3N3O3/c1-2-28-15(27)10-7-23-25(12(10)16(20,21)22)9-5-3-8(4-6-9)24-14(26)11(17)13(18)19/h3-7H,2H2,1H3,(H,24,26)
    Synonyms
    J-003374 | AKOS024457787 | 1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4...
  4. GSK 2193874, Channel blocker of TRPV4
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    GSK 2193874, Channel blocker of TRPV4
    CAS: 1336960-13-4 EC Number: 808-437-6 Formula: C37H38BrF3N4O Molecular Weight: 691.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G421274
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    Technical Identifiers
    IUPAC Name
    7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
    SMILES
    C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7
    InChIKey
    UIVOZBSCHXCGPS-UHFFFAOYSA-N
    InChI
    1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36show more
    Synonyms
    GSK2193874 | GSK-2193874 | GTPL6465 | NCGC00370767-01 | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopr...
  5. SAR7334 - Moligand™, ≥97% CAS No(1333210-07-3) by Aladdin Scientific
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    SAR7334, Channel blocker of TRPC3;Channel blocker of TRPC6;Channel blocker of TRPC7
    CAS: 1333210-07-3 PubChem CID: 53378752 Formula: C21H22ClN3O Molecular Weight: 367.87
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: S413561
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    IUPAC Name
    4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile
    SMILES
    C1CC(CN(C1)C2CC3=CC=CC=C3C2OC4=C(C=C(C=C4)C#N)Cl)N
    InChIKey
    RLKRLNQEXBPQGQ-OZOXKJRCSA-N
    InChI
    1S/C21H22ClN3O/c22-18-10-14(12-23)7-8-20(18)26-21-17-6-2-1-4-15(17)11-19(21)25-9-3-5-16(24)13-25/h1-2,4,6-8,10,16,19,21H,3,5,9,11,13,24H2/t16-,19-,21-show more
    Synonyms
    Benzonitrile | 4-​[[(1R,​2R)​-​2-​[(3R)​-​3-​amino-​1-​piperidinyl]​-​2,​3-​dihydro-​1H-​inden-​1-​yl]​oxy]​-​3-​chlo...
  6. SAR7334, Channel blocker of TRPC3;Channel blocker of TRPC6;Channel blocker of TRPC7
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    SAR7334, Channel blocker of TRPC3;Channel blocker of TRPC6;Channel blocker of TRPC7
    CAS: 1333210-07-3 PubChem CID: 53378752 Formula: C21H22ClN3O Molecular Weight: 367.87
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: S421260
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    Technical Identifiers
    IUPAC Name
    4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile
    SMILES
    C1CC(CN(C1)C2CC3=CC=CC=C3C2OC4=C(C=C(C=C4)C#N)Cl)N
    InChIKey
    RLKRLNQEXBPQGQ-OZOXKJRCSA-N
    InChI
    1S/C21H22ClN3O/c22-18-10-14(12-23)7-8-20(18)26-21-17-6-2-1-4-15(17)11-19(21)25-9-3-5-16(24)13-25/h1-2,4,6-8,10,16,19,21H,3,5,9,11,13,24H2/t16-,19-,21-show more
    Synonyms
    Benzonitrile | 4-​[[(1R,​2R)​-​2-​[(3R)​-​3-​amino-​1-​piperidinyl]​-​2,​3-​dihydro-​1H-​inden-​1-​yl]​oxy]​-​3-​chlo...
  7. YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    Wish List Compare
    YM-58483 (BTP2）, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
    CAS: 223499-30-7 EC Number: 636-569-2 PubChem CID: 2455 Formula: C15H9F6N5OS Molecular Weight: 421.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: Y422686
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
    SMILES
    CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    XPRZIORDEVHURQ-UHFFFAOYSA-N
    InChI
    1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
    Synonyms
    HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | I...
  8. no_selection
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    M084, Channel blocker of TRPC4;Channel blocker of TRPC5
    CAS: 51314-51-3 EC Number: 899-536-3 Formula: C11H15N3 Molecular Weight: 189.26
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    Out of Stock Item #: M611698
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    Technical Identifiers
    IUPAC Name
    N-butyl-1H-benzimidazol-2-amine
    SMILES
    CCCCNc1nc2c([nH]1)cccc2
    InChIKey
    OKKUCNXCFWODOE-UHFFFAOYSA-N
    InChI
    1S/C11H15N3/c1-2-3-8-12-11-13-9-6-4-5-7-10(9)14-11/h4-7H,2-3,8H2,1H3,(H2,12,13,14)
    Synonyms
    MLS000567651 | HMS1719N18 | DTXSID20965602 | NSC 139486 | HMS2275D04 | BCA31451 | GTPL10288 | SCHEMBL22619945 | Q2721...
  9. no_selection
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    Pyr10, Channel blocker of TRPC3
    CAS: 1315323-00-2 EC Number: 808-921-7 PubChem CID: 53475435 Formula: C18H13F6N3O2S Molecular Weight: 449.37
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: P613023
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide
    SMILES
    CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    CVALMMCIOLXHDM-UHFFFAOYSA-N
    InChI
    1S/C18H13F6N3O2S/c1-11-2-8-14(9-3-11)30(28,29)26-12-4-6-13(7-5-12)27-16(18(22,23)24)10-15(25-27)17(19,20)21/h2-10,26H,1H3
    Synonyms
    EX-A3814 | N-{4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}-4-methylbenzenesulfonamide | F85327 | HY-19408 | AK...
  10. Pyr6 - Moligand™,≥99% CAS No(245747-08-4) by Aladdin Scientific
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    Pyr6
    CAS: 245747-08-4 EC Number: 808-615-3 PubChem CID: 10598093 Formula: C17H9F7N4O Molecular Weight: 418.27
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Out of Stock Item #: P646980
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    Technical Identifiers
    IUPAC Name
    N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-3-fluoropyridine-4-carboxamide
    SMILES
    C1=CC(=CC=C1NC(=O)C2=C(C=NC=C2)F)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
    InChIKey
    XZIQSOZOLJJMFN-UHFFFAOYSA-N
    InChI
    1S/C17H9F7N4O/c18-12-8-25-6-5-11(12)15(29)26-9-1-3-10(4-2-9)28-14(17(22,23)24)7-13(27-28)16(19,20)21/h1-8H,(H,26,29)
    Synonyms
    AKOS030526749 | XZIQSOZOLJJMFN-UHFFFAOYSA-N | BDBM50450630 | PYR6 | n-[4-[3,5-bis(trifluoromethyl)-1h-pyrazol-1-yl]ph...
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