Ephrin type-a receptor 3 (EPHA3)

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  1. NVP-BHG712
    CAS: 940310-85-0 EC Number: 804-395-8 Formula: C26H20F3N7O Molecular Weight: 503.48
    In Stock Item #: N127928
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    IUPAC Name
    4-methyl-3-[(1-methyl-6-pyridin-3-ylpyrazolo[3,4-d]pyrimidin-4-yl)amino]-N-[3-(trifluoromethyl)phenyl]benzamide
    SMILES
    CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=C4C=NN(C4=NC(=N3)C5=CN=CC=C5)C
    InChIKey
    ZCCPLJOKGAACRT-UHFFFAOYSA-N
    InChI
    1S/C26H20F3N7O/c1-15-8-9-16(25(37)32-19-7-3-6-18(12-19)26(27,28)29)11-21(15)33-23-20-14-31-36(2)24(20)35-22(34-23)17-5-4-10-30-13-17/h3-14H,1-2H3,(H,3show more
    Synonyms
    4-Methyl-3-(1-methyl-6-pyridin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-trifluoromethyl-phenyl)-benzamide | B...
  2. ALW-II-41-27
    CAS: 1186206-79-0 Formula: C32H32F3N5O2S Molecular Weight: 607.69
    In Stock Item #: A127683
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    IUPAC Name
    N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F
    InChIKey
    HYWXBDQAYLPMIX-UHFFFAOYSA-N
    InChI
    1S/C32H32F3N5O2S/c1-3-39-10-12-40(13-11-39)20-23-8-9-26(17-27(23)32(33,34)35)37-30(41)22-7-6-21(2)28(16-22)38-31(42)25-15-24(18-36-19-25)29-5-4-14-43-show more
    Synonyms
    EX-A2618 | ALW-II-41-27 | HMS3333E20 | BCP26205 | HMS2043H01 | HY-18007 | SCHEMBL20136698 | N-[5-({4-[(4-Ethylpiperaz...
  3. Dasatinib(BMS-354825), Bcr/Abl fusion protein
    CAS: 302962-49-8 EC Number: 801-607-0 Formula: C22H26ClN7O2S Molecular Weight: 488.01
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: D125110
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    IUPAC Name
    N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
    SMILES
    CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO
    InChIKey
    ZBNZXTGUTAYRHI-UHFFFAOYSA-N
    InChI
    1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(Hshow more
    Synonyms
    BMS 354825 | AR-270/43507994 | Dasatinib (JAN/INN) | HMS3744C11 | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHY...
  4. Dasatinib (monohydrate)
    CAS: 863127-77-9 EC Number: 638-874-6 Formula: C22H26ClN7O2S • (H2O) Molecular Weight: 506.03
    In Stock Item #: D341181
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    Technical Identifiers
    IUPAC Name
    N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;hydrate
    SMILES
    CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O
    InChIKey
    XHXFZZNHDVTMLI-UHFFFAOYSA-N
    InChI
    1S/C22H26ClN7O2S.H2O/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31;/h3-5,12-13,31H,6-11H2,1-2show more
    Synonyms
    AM20030145 | dasatinib.H2O | A16320 | N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpy...
  5. ALW-II-41-27
    CAS: 1186206-79-0 Formula: C32H32F3N5O2S Molecular Weight: 607.69
    10mM in DMSO
    In Stock Item #: A420821
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    Technical Identifiers
    IUPAC Name
    N-[5-[[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]-5-thiophen-2-ylpyridine-3-carboxamide
    SMILES
    CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)NC(=O)C4=CN=CC(=C4)C5=CC=CS5)C(F)(F)F
    InChIKey
    HYWXBDQAYLPMIX-UHFFFAOYSA-N
    InChI
    1S/C32H32F3N5O2S/c1-3-39-10-12-40(13-11-39)20-23-8-9-26(17-27(23)32(33,34)35)37-30(41)22-7-6-21(2)28(16-22)38-31(42)25-15-24(18-36-19-25)29-5-4-14-43-show more
    Synonyms
    ALW-II-41-27|1186206-79-0|N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)carbamoyl)-2-methylpheny...
  6. Dasatinib (monohydrate)
    CAS: 863127-77-9 EC Number: 638-874-6 Formula: C22H26ClN7O2S • (H2O) Molecular Weight: 506.03
    10mM in DMSO
    In Stock Item #: D426403
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;hydrate
    SMILES
    CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O
    InChIKey
    XHXFZZNHDVTMLI-UHFFFAOYSA-N
    InChI
    1S/C22H26ClN7O2S.H2O/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31;/h3-5,12-13,31H,6-11H2,1-2show more
    Synonyms
    AM20030145 | dasatinib.H2O | A16320 | N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpy...
  7. Dasatinib (BMS-354825), Bcr/Abl fusion protein
    CAS: 302962-49-8 EC Number: 801-607-0 Formula: C22H26ClN7O2S Molecular Weight: 488.01
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: D407815
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    Technical Identifiers
  8. NVP-BHG712
    CAS: 940310-85-0 EC Number: 804-395-8 Formula: C26H20F3N7O Molecular Weight: 503.48
    10mM in DMSO
    In Stock Item #: N408613
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    Pricing & Pack Sizes
    Technical Identifiers
    Synonyms
    4-methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide
  9. 5-[2-[5-[[4-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]ethynyl]-N,1-dimethylimidazole-2-carboxamide, Inhibitor of ABL proto-oncogene 1; non-receptor tyrosine kinase;Inhibitor of EPH receptor A2;Inhibitor of EPH receptor A3;Inhibitor of EPH receptor A7;Inhibitor of platelet derived growth factor receptor alpha;Inhibitor of ret proto-oncogene;Inhibitor of
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: H609459
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    5-[2-[5-[[4-[[4-(2-hydroxyethyl)piperazin-1-yl]methyl]-3-(trifluoromethyl)phenyl]carbamoyl]-2-methylphenyl]ethynyl]-N,1-dimethylimidazole-2-carboxamidshow more
    SMILES
    OCCN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)c1ccc(c(c1)C#Cc1cnc(n1C)C(=O)NC)C
    InChIKey
    SUXYGJZMCWKJJI-UHFFFAOYSA-N
    InChI
    1S/C30H33F3N6O3/c1-20-4-5-22(16-21(20)7-9-25-18-35-27(37(25)3)29(42)34-2)28(41)36-24-8-6-23(26(17-24)30(31,32)33)19-39-12-10-38(11-13-39)14-15-40/h4-6show more
    Synonyms
    compound 8h
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