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Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)

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  1. GSK PERK inhibitor, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3;Inhibitor of myosin light chain kinase 2
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    GSK PERK inhibitor, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3;Inhibitor of myosin light chain kinase 2
    CAS: 1337531-89-1 Formula: C24H19F4N5O Molecular Weight: 469.43
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G355474
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone
    SMILES
    CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC(=C5)F)C(F)(F)F
    InChIKey
    PXVQGBJMIQCDEX-UHFFFAOYSA-N
    InChI
    1S/C24H19F4N5O/c1-32-11-18(21-22(29)30-12-31-23(21)32)14-2-3-19-15(9-14)4-5-33(19)20(34)8-13-6-16(24(26,27)28)10-17(25)7-13/h2-3,6-7,9-12H,4-5,8H2,1H3show more
    Synonyms
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2, 3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]eth...
  2. GSK2606414 - Moligand™, ≥98% CAS No(1337531-36-8) by Aladdin Scientific
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    GSK2606414
    CAS: 1337531-36-8 Formula: C24H20F3N5O Molecular Weight: 451.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G125654
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
    SMILES
    CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
    InChIKey
    SIXVRXARNAVBTC-UHFFFAOYSA-N
    InChI
    1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25,26)27/h2-6,9,11-13H,7-8,10H2,1H3,(Hshow more
    Synonyms
    AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
  3. GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
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    GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
    CAS: 1337532-29-2 Formula: C23H21FN6O Molecular Weight: 416.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: G276179
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    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    SMILES
    CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
    InChIKey
    PRWSIEBRGXYXAJ-UHFFFAOYSA-N
    InChI
    1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,2show more
    Synonyms
    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
  4. 6'-Amino-3',4'-(methylenedioxy)acetophenone
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    6'-Amino-3',4'-(methylenedioxy)acetophenone
    CAS: 28657-75-2 EC Number: 249-131-7 Formula: C9H9NO3 Molecular Weight: 179.18
    ≥98%
    In Stock Item #: A151774
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    IUPAC Name
    1-(6-amino-1,3-benzodioxol-5-yl)ethanone
    SMILES
    CC(=O)C1=CC2=C(C=C1N)OCO2
    InChIKey
    DWTHYSZSRJOMSC-UHFFFAOYSA-N
    InChI
    1S/C9H9NO3/c1-5(11)6-2-8-9(3-7(6)10)13-4-12-8/h2-3H,4,10H2,1H3
    Synonyms
    2'-Amino-4',5'-methylenedioxyacetophenone | 2-Amino-4,5-methylenedioxyacetophenone | A819522 | HMS2424B23 | Misoprost...
  5. Nexinhib20, Inhibitor of RAB27A; member RAS oncogene family
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    Nexinhib20, Inhibitor of RAB27A; member RAS oncogene family
    CAS: 331949-35-0 Formula: C15H16N4O3 Molecular Weight: 300.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: N287850
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    IUPAC Name
    (Z)-4,4-dimethyl-1-(3-nitrophenyl)-2-(1,2,4-triazol-1-yl)pent-1-en-3-one
    SMILES
    CC(C)(C)C(=O)C(=CC1=CC(=CC=C1)[N+](=O)[O-])N2C=NC=N2
    InChIKey
    VKSOIYNNOFGGES-JYRVWZFOSA-N
    InChI
    1S/C15H16N4O3/c1-15(2,3)14(20)13(18-10-16-9-17-18)8-11-5-4-6-12(7-11)19(21)22/h4-10H,1-3H3/b13-8-
    Synonyms
    4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one | 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-...
  6. 5-Amino-3-methylisothiazole-4-carboxylic acid
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    5-Amino-3-methylisothiazole-4-carboxylic acid
    CAS: 22131-51-7 EC Number: 800-176-6 Formula: C5H6N2O2S Molecular Weight: 158.2
    ≥95%
    Out of Stock Item #: A182910
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    IUPAC Name
    5-amino-3-methyl-1,2-thiazole-4-carboxylic acid
    SMILES
    CC1=NSC(=C1C(=O)O)N
    InChIKey
    AQBUEVXOULPURO-UHFFFAOYSA-N
    InChI
    1S/C5H6N2O2S/c1-2-3(5(8)9)4(6)10-7-2/h6H2,1H3,(H,8,9)
    Synonyms
    TQR0286 | NCGC00246176-01 | HMS2768J15 | SMR000365258 | EN300-14305 | Z314790180 | 3-Methyl-5-aminoisothiazolo-4-carb...
  7. 2-Hydroxy-5-methyl-3-nitropyridine
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    2-Hydroxy-5-methyl-3-nitropyridine
    CAS: 7464-14-4 EC Number: 625-895-0 Formula: C6H6N2O3 Molecular Weight: 154.12
    ≥97%
    In Stock Item #: H121607
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    Technical Identifiers
    IUPAC Name
    5-methyl-3-nitro-1H-pyridin-2-one
    SMILES
    CC1=CNC(=O)C(=C1)[N+](=O)[O-]
    InChIKey
    QAINEQVHSHARMD-UHFFFAOYSA-N
    InChI
    1S/C6H6N2O3/c1-4-2-5(8(10)11)6(9)7-3-4/h2-3H,1H3,(H,7,9)
    Synonyms
    AI3-52332 | H1483 | QAINEQVHSHARMD-UHFFFAOYSA-N | 5-methyl-3-nitro-1H-pyridone | 5-methyl-3-nitro-pyridin-2-ol | 5-me...
  8. GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
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    GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
    CAS: 1337532-29-2 Formula: C23H21FN6O Molecular Weight: 416.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G421276
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    Technical Identifiers
    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    SMILES
    CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
    InChIKey
    PRWSIEBRGXYXAJ-UHFFFAOYSA-N
    InChI
    1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,2show more
    Synonyms
    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
  9. GSK2606414
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    GSK2606414
    CAS: 1337531-36-8 Formula: C24H20F3N5O Molecular Weight: 451.44
    10mM in DMSO
    In Stock Item #: G421275
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    Technical Identifiers
    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
    SMILES
    CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
    InChIKey
    SIXVRXARNAVBTC-UHFFFAOYSA-N
    InChI
    1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25,26)27/h2-6,9,11-13H,7-8,10H2,1H3,(Hshow more
    Synonyms
    AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
  10. WAY-217905
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    WAY-217905
    CAS: 442554-18-9 PubChem CID: 656005 Formula: C8H15N5O Molecular Weight: 197.24
    10mM in DMSO
    Out of Stock Item #: W423996
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    IUPAC Name
    5-[2-(dimethylamino)ethylamino]-6-methyl-2H-1,2,4-triazin-3-one
    SMILES
    CC1=NNC(=O)N=C1NCCN(C)C
    InChIKey
    PBMFJQHGZTXUDY-UHFFFAOYSA-N
    InChI
    1S/C8H15N5O/c1-6-7(9-4-5-13(2)3)10-8(14)12-11-6/h4-5H2,1-3H3,(H2,9,10,12,14)
  11. no_selection
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    GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: G610708
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    Technical Identifiers
    IUPAC Name
    1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
    SMILES
    O=C(N1CCc2c1ccc(c2F)c1cn(c2c1c(N)ncn2)C)Cc1cccc(n1)C
    InChIKey
    PRWSIEBRGXYXAJ-UHFFFAOYSA-N
    InChI
    1S/C23H21FN6O/c1-13-4-3-5-14(28-13)10-19(31)30-9-8-16-18(30)7-6-15(21(16)24)17-11-29(2)23-20(17)22(25)26-12-27-23/h3-7,11-12H,8-10H2,1-2H3,(H2,25,26,2show more
    Synonyms
    1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
  12. no_selection
    Wish List Compare
    Nexinhib20, Inhibitor of RAB27A; member RAS oncogene family
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: N612275
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    Technical Identifiers
    IUPAC Name
    (Z)-4,4-dimethyl-1-(3-nitrophenyl)-2-(1,2,4-triazol-1-yl)pent-1-en-3-one
    SMILES
    O=C(C(C)(C)C)/C(=C/c1cccc(c1)[N+](=O)[O-])/n1cncn1
    InChIKey
    VKSOIYNNOFGGES-JYRVWZFOSA-N
    InChI
    1S/C15H16N4O3/c1-15(2,3)14(20)13(18-10-16-9-17-18)8-11-5-4-6-12(7-11)19(21)22/h4-10H,1-3H3/b13-8-
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