Misshapen-like kinase 1 (MINK1)

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  1. LY2157299, TGF-beta receptor type I inhibitor
    CAS: 700874-72-2 EC Number: 142-220-0 Formula: C22H19N5O Molecular Weight: 369.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: L126937
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    IUPAC Name
    4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide
    SMILES
    CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
    InChIKey
    IVRXNBXKWIJUQB-UHFFFAOYSA-N
    InChI
    1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
    Synonyms
    BDBM50015640 | 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline-6-carboxamide | MFCD00...
  2. MMV-390048
    CAS: 1314883-11-8 Formula: C18H14F3N3O2S Molecular Weight: 393.383
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: M173331
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    IUPAC Name
    5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)pyridin-3-yl]pyridin-2-amine
    SMILES
    CS(=O)(=O)C1=CC=C(C=C1)C2=CC(=C(N=C2)N)C3=CN=C(C=C3)C(F)(F)F
    InChIKey
    RTJQABCNNLMCJF-UHFFFAOYSA-N
    InChI
    1S/C18H14F3N3O2S/c1-27(25,26)14-5-2-11(3-6-14)13-8-15(17(22)24-10-13)12-4-7-16(23-9-12)18(19,20)21/h2-10H,1H3,(H2,22,24)
    Synonyms
    0Z5T00JJ10 | AKOS030628490 | SCHEMBL2225969 | 3-(2-(Trifluoromethyl)pyridin-5-yl)-5-(4-(methylsulfonyl)- phenyl)pyrid...
  3. Mubritinib (TAK 165), Receptor protein-tyrosine kinase erbB-2 inhibitor
    CAS: 366017-09-6 Formula: C25H23F3N4O2 Molecular Weight: 468.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: M129797
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    IUPAC Name
    4-[[4-[4-(triazol-1-yl)butyl]phenoxy]methyl]-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
    SMILES
    C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F
    InChIKey
    ZTFBIUXIQYRUNT-MDWZMJQESA-N
    InChI
    1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13show more
    Synonyms
    TAK165 | DNDI1268116 | M3058 | SCHEMBL50451 | CCG-269433 | Mubritinib (USAN/INN) | D04025 | DTXSID501026014 | [4-[4-[...
  4. SKI II, Inhibitor of delta 4-desaturase; sphingolipid 1;Inhibitor of sphingosine kinase 1;Inhibitor of sphingosine kinase 2
    CAS: 312636-16-1 PubChem CID: 753704 Formula: C15H11ClN2OS Molecular Weight: 302.78
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S129855
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    IUPAC Name
    4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]phenol
    SMILES
    C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
    InChIKey
    ZFGXZJKLOFCECI-UHFFFAOYSA-N
    InChI
    1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)
    Synonyms
    CCG-265019 | HMS3413G03 | SKI II | Ski ii (sphk-i2) | HMS3650M12 | NCGC00092309-01 | SKI 2 | BDBM50312869 | HMS3677G0...
  5. GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
    CAS: 905281-76-7 Formula: C19H18N4O2 Molecular Weight: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%
    In Stock Item #: G127893
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    IUPAC Name
    2-[4-[(1E)-1-hydroxyimino-2,3-dihydroinden-5-yl]-3-pyridin-4-ylpyrazol-1-yl]ethanol
    SMILES
    C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO
    InChIKey
    DEZZLWQELQORIU-RELWKKBWSA-N
    InChI
    1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+
    Synonyms
    SCHEMBL2467603 | 2,3-dihydro-5-(1-(2-hydroxyethyl)-3-(4-pyridinyl)-1h-pyrazol-4-yl)-1h-inden-1-one oxime | CCG-264821...
  6. TAK-715, MAP kinase p38 alpha inhibitor
    CAS: 303162-79-0 EC Number: 803-674-1 PubChem CID: 9952773 Formula: C24H21N3OS Molecular Weight: 399.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: T125460
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    IUPAC Name
    N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]benzamide
    SMILES
    CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC(=C4)C
    InChIKey
    HEKAIDKUDLCBRU-UHFFFAOYSA-N
    InChI
    1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)
    Synonyms
    N-(4-(2-Ethyl-4-m-Tolylthazol-5-yl)pyrdn-2-yl)benzamde | HMS3265L10 | Kinome_2655 | MLS006011241 | BCPP000054 | HB059...
  7. SB 239063
    CAS: 193551-21-2 PubChem CID: 5166 Formula: C20H21N4O2F Molecular Weight: 368.4
    In Stock Item #: S133266
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    IUPAC Name
    4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazol-1-yl]cyclohexan-1-ol
    SMILES
    COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F
    InChIKey
    ZQUSFAUAYSEREK-UHFFFAOYSA-N
    InChI
    1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3
    Synonyms
    4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1-imidazolyl]-1-cyclohexanol | 4-[4-(4-fluorophenyl)-5-(2-methoxypy...
  8. GDC-0879, Inhibitor of B-Raf proto-oncogene; serine/threonine kinase
    CAS: 905281-76-7 Formula: C19H18N4O2 Molecular Weight: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G409101
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    Synonyms
    AR-00341677 | (E)-5-(1-(2-hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydroinden-1-one oxime
  9. Galunisertib (LY2157299), TGF-beta receptor type I inhibitor
    CAS: 700874-72-2 EC Number: 142-220-0 Formula: C22H19N5O Molecular Weight: 369.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: G407839
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    Technical Identifiers
    Synonyms
    4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide
  10. Mubritinib (TAK 165), Receptor protein-tyrosine kinase erbB-2 inhibitor
    CAS: 366017-09-6 Formula: C25H23F3N4O2 Molecular Weight: 468.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: M409057
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    Technical Identifiers
    Synonyms
    (E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole
  11. PF-6260933
    CAS: 1811510-56-1 PubChem CID: 118701008 Formula: C16H13ClN4 Molecular Weight: 296.75
    10mM in DMSO
    In Stock Item #: P422224
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    IUPAC Name
    5-(6-aminopyridin-3-yl)-3-(4-chlorophenyl)pyridin-2-amine
    SMILES
    C1=CC(=CC=C1C2=C(N=CC(=C2)C3=CN=C(C=C3)N)N)Cl
    InChIKey
    KHPCIHZXOGHCLY-UHFFFAOYSA-N
    InChI
    1S/C16H13ClN4/c17-13-4-1-10(2-5-13)14-7-12(9-21-16(14)19)11-3-6-15(18)20-8-11/h1-9H,(H2,18,20)(H2,19,21)
    Synonyms
    PF-06260933[3,​3'-​Bipyridine]​-​6,​6'-​diamine,5-​(4-​chlorophenyl)​-
  12. PF-6260933
    CAS: 1811510-56-1 PubChem CID: 118701008 Formula: C16H13ClN4 Molecular Weight: 296.75
    In Stock Item #: P413486
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    Technical Identifiers
    IUPAC Name
    5-(6-aminopyridin-3-yl)-3-(4-chlorophenyl)pyridin-2-amine
    SMILES
    C1=CC(=CC=C1C2=C(N=CC(=C2)C3=CN=C(C=C3)N)N)Cl
    InChIKey
    KHPCIHZXOGHCLY-UHFFFAOYSA-N
    InChI
    1S/C16H13ClN4/c17-13-4-1-10(2-5-13)14-7-12(9-21-16(14)19)11-3-6-15(18)20-8-11/h1-9H,(H2,18,20)(H2,19,21)
    Synonyms
    PF-06260933[3,​3'-​Bipyridine]​-​6,​6'-​diamine,5-​(4-​chlorophenyl)​-
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