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Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3)

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  1. Spautin-1
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    Spautin-1
    CAS: 1262888-28-7 EC Number: 802-904-8 PubChem CID: 51037431 Formula: C15H11F2N3 Molecular Weight: 271.26
    ≥98%(HPLC)
    In Stock Item #: S166799
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    Technical Identifiers
    IUPAC Name
    6-fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
    SMILES
    C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F
    InChIKey
    AWIVHRPYFSSVOG-UHFFFAOYSA-N
    InChI
    1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20)
    Synonyms
    A889470 | CS1815 | MBCQ derivative C43 | NCGC00263555-05 | deoxy-ATP, 2'-deoxyadenosine triphosphate, Deoxyadenosine ...
  2. Panobinostat (LBH589), Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 3;Inhibitor of histone deacetylase 4;Inhibitor of histone deacetylase 6;Inhibitor of histone deacetylase 7;Inhibitor of histone deacetylase 8;Inhibitor
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    Panobinostat (LBH589), Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 3;Inhibitor of histone deacetylase 4;Inhibitor of histone deacetylase 6;Inhibitor of histone deacetylase 7;Inhibitor of histone deacetylase 8;Inhibitor
    CAS: 404950-80-7 EC Number: 803-814-1 Formula: C21H23N3O2 Molecular Weight: 349.44
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: P125167
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    IUPAC Name
    (E)-N-hydroxy-3-[4-[[2-(2-methyl-1H-indol-3-yl)ethylamino]methyl]phenyl]prop-2-enamide
    SMILES
    CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)C=CC(=O)NO
    InChIKey
    FPOHNWQLNRZRFC-ZHACJKMWSA-N
    InChI
    1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+
    Synonyms
    BCP01816 | Panobinostat(LBH589) | AM808102 | GTPL7489 | NSC 108217 | AKOS005146046 | N-Hydroxy-3-[4-[2-(2-methyl-1H-i...
  3. Wortmannin - Moligand™, ≥98% CAS No(19545-26-7) by Aladdin Scientific
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    Wortmannin, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
    CAS: 19545-26-7 EC Number: 606-337-5 PubChem CID: 312145 Formula: C23H24O8 Molecular Weight: 428.43
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: W100984
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    IUPAC Name
    [(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),12(19),14-trien-3-yl] show more
    SMILES
    CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C
    InChIKey
    QDLHCMPXEPAAMD-QAIWCSMKSA-N
    InChI
    1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15show more
    Synonyms
    BRN 0067676 | SCHEMBL4531 | ST-415 | (1S,6bR,9aS,11R,11bR)-1-(methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-3,6,6b,7,8,...
  4. SAR-405, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3
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    SAR-405, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3
    CAS: 1523406-39-4 Formula: C19H21ClF3N5O2 Molecular Weight: 443.85
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Out of Stock Item #: S174388
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    IUPAC Name
    (8S)-9-[(5-chloropyridin-3-yl)methyl]-2-[(3R)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one
    SMILES
    CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F
    InChIKey
    SPDQRCUBFSRAFI-DOMZBBRYSA-N
    InChI
    1S/C19H21ClF3N5O2/c1-12-11-30-5-4-26(12)16-7-17(29)27-3-2-15(19(21,22)23)28(18(27)25-16)10-13-6-14(20)9-24-8-13/h6-9,12,15H,2-5,10-11H2,1H3/t12-,15+/mshow more
    Synonyms
    (S)-9-((5-Chloropyridin-3-yl)methyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,...
  5. Autophinib
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    Autophinib
    CAS: 1644443-47-9 Formula: C14H11ClN6O3 Molecular Weight: 346.73
    ≥98%(HPLC)
    In Stock Item #: A286631
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    IUPAC Name
    6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine
    SMILES
    CC1=CC(=NN1)NC2=CC(=NC(=N2)OC3=CC=C(C=C3)[N+](=O)[O-])Cl
    InChIKey
    CEUMAXLRGBKFQP-UHFFFAOYSA-N
    InChI
    1S/C14H11ClN6O3/c1-8-6-13(20-19-8)17-12-7-11(15)16-14(18-12)24-10-4-2-9(3-5-10)21(22)23/h2-7H,1H3,(H2,16,17,18,19,20)
    Synonyms
    6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine | 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(...
  6. KU 60019
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    KU 60019
    CAS: 925701-46-8 Formula: C30H33N3O5S Molecular Weight: 547.67
    ≥98%
    Out of Stock Item #: K335691
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    IUPAC Name
    2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-9H-thioxanthen-2-yl]acetamide
    SMILES
    CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C3)C=CC=C4C5=CC(=O)C=C(O5)N6CCOCC6
    InChIKey
    SCELLOWTHJGVIC-BGYRXZFFSA-N
    InChI
    1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-show more
    Synonyms
    KU-60019, >=98% (HPLC) | SW219699-1 | 2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-...
  7. KU-60019, Inhibitor of ATM serine/threonine kinase
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    KU-60019, Inhibitor of ATM serine/threonine kinase
    CAS: 925701-49-1 Formula: C30H33N3O5S Molecular Weight: 547.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K127121
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    Technical Identifiers
    IUPAC Name
    2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-9H-thioxanthen-2-yl]acetamide
    SMILES
    CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C3)C=CC=C4C5=CC(=O)C=C(O5)N6CCOCC6
    InChIKey
    SCELLOWTHJGVIC-BGYRXZFFSA-N
    InChI
    1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-show more
    Synonyms
    KU-60019, >=98% (HPLC) | SW219699-1 | 2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-N-[5-(6-morpholin-4-yl-4-oxopyran-2-yl)-...
  8. Autophinib
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    Autophinib
    CAS: 1644443-47-9 Formula: C14H11ClN6O3 Molecular Weight: 346.73
    10mM in DMSO
    In Stock Item #: A422037
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    Technical Identifiers
    IUPAC Name
    6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine
    SMILES
    CC1=CC(=NN1)NC2=CC(=NC(=N2)OC3=CC=C(C=C3)[N+](=O)[O-])Cl
    InChIKey
    CEUMAXLRGBKFQP-UHFFFAOYSA-N
    InChI
    1S/C14H11ClN6O3/c1-8-6-13(20-19-8)17-12-7-11(15)16-14(18-12)24-10-4-2-9(3-5-10)21(22)23/h2-7H,1H3,(H2,16,17,18,19,20)
    Synonyms
    6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)pyrimidin-4-amine | 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(...
  9. KU-60019, Inhibitor of ATM serine/threonine kinase
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    KU-60019, Inhibitor of ATM serine/threonine kinase
    CAS: 925701-49-1 Formula: C30H33N3O5S Molecular Weight: 547.68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: K408825
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    Technical Identifiers
    Synonyms
    2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide
  10. KDU691
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    KDU691
    CAS: 1513879-19-0 Formula: C22H18ClN5O2 Molecular Weight: 419.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: K421794
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    IUPAC Name
    N-(4-chlorophenyl)-N-methyl-3-[4-(methylcarbamoyl)phenyl]imidazo[1,2-a]pyrazine-6-carboxamide
    SMILES
    CNC(=O)C1=CC=C(C=C1)C2=CN=C3N2C=C(N=C3)C(=O)N(C)C4=CC=C(C=C4)Cl
    InChIKey
    TYMFFISSODJRDV-UHFFFAOYSA-N
    InChI
    1S/C22H18ClN5O2/c1-24-21(29)15-5-3-14(4-6-15)19-11-26-20-12-25-18(13-28(19)20)22(30)27(2)17-9-7-16(23)8-10-17/h3-13H,1-2H3,(H,24,29)
    Synonyms
    Imidazo[1,​2-​a]​pyrazine-​6-​carboxamide,N-​(4-​chlorophenyl)​-​N-​methyl-​3-​[4-​[(methylamino)​carbonyl]​phenyl]​-
  11. KDU691
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    KDU691
    CAS: 1513879-19-0 Formula: C22H18ClN5O2 Molecular Weight: 419.86
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: K413526
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    Technical Identifiers
    IUPAC Name
    N-(4-chlorophenyl)-N-methyl-3-[4-(methylcarbamoyl)phenyl]imidazo[1,2-a]pyrazine-6-carboxamide
    SMILES
    CNC(=O)C1=CC=C(C=C1)C2=CN=C3N2C=C(N=C3)C(=O)N(C)C4=CC=C(C=C4)Cl
    InChIKey
    TYMFFISSODJRDV-UHFFFAOYSA-N
    InChI
    1S/C22H18ClN5O2/c1-24-21(29)15-5-3-14(4-6-15)19-11-26-20-12-25-18(13-28(19)20)22(30)27(2)17-9-7-16(23)8-10-17/h3-13H,1-2H3,(H,24,29)
    Synonyms
    Imidazo[1,​2-​a]​pyrazine-​6-​carboxamide,N-​(4-​chlorophenyl)​-​N-​methyl-​3-​[4-​[(methylamino)​carbonyl]​phenyl]​-...
  12. ML162
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    ML162
    CAS: 1035072-16-2 EC Number: 188-421-7 Formula: C23H22Cl2N2O3S Molecular Weight: 477.4
    10mM in DMSO
    In Stock Item #: M420426
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    IUPAC Name
    2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide
    SMILES
    COC1=C(C=C(C=C1)N(C(C2=CC=CS2)C(=O)NCCC3=CC=CC=C3)C(=O)CCl)Cl
    InChIKey
    UNVKYJSNMVDZJE-UHFFFAOYSA-N
    InChI
    1S/C23H22Cl2N2O3S/c1-30-19-10-9-17(14-18(19)25)27(21(28)15-24)22(20-8-5-13-31-20)23(29)26-12-11-16-6-3-2-4-7-16/h2-10,13-14,22H,11-12,15H2,1H3,(H,26,2show more
    Synonyms
    BRD-5421 | Molecular Libraries 162
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