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PCSK9

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  1. Anacetrapib, Cholesteryl ester transfer protein inhibitor
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    Anacetrapib, Cholesteryl ester transfer protein inhibitor
    CAS: 875446-37-0 EC Number: 810-468-5 Formula: C30H25F10NO3 Molecular Weight: 637.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: A127068
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    Technical Identifiers
    IUPAC Name
    (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-show more
    SMILES
    CC1C(OC(=O)N1CC2=C(C=CC(=C2)C(F)(F)F)C3=CC(=C(C=C3OC)F)C(C)C)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F
    InChIKey
    MZZLGJHLQGUVPN-HAWMADMCSA-N
    InChI
    1S/C30H25F10NO3/c1-14(2)22-11-23(25(43-4)12-24(22)31)21-6-5-18(28(32,33)34)9-17(21)13-41-15(3)26(44-27(41)42)16-7-19(29(35,36)37)10-20(8-16)30(38,39)4show more
    Synonyms
    Anacetrapib - MK-0859 | s2748 | KBio3_001100 | MLS006010190 | A24886 | BDBM50348228 | STL554443 | Anacetrapib (JAN/US...
  2. Pep 2-8
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    Pep 2-8
    CAS: 1541011-97-5 PubChem CID: 124221781 Formula: C83H110N16O24 Molecular Weight: 1715.88
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: P286980
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    Technical Identifiers
    IUPAC Name
    (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-acetamido-3-hydroxybutanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoshow more
    SMILES
    CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C(C)C)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC4=CNC5=CC=show more
    InChIKey
    ORPZALWAWWEEDP-NXXUBLNKSA-N
    InChI
    1S/C83H110N16O24/c1-40(2)31-57(74(114)94-62(36-66(109)110)77(117)92-61(79(119)97-67(41(3)4)71(84)111)35-49-38-86-54-22-16-14-20-52(49)54)90-75(115)58(show more
  3. 2-Hydroxy-5-methoxy-3-undecyl-[1,4]benzoquinone
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    2-Hydroxy-5-methoxy-3-undecyl-[1,4]benzoquinone
    CAS: 56005-10-8 Formula: C18H28O4 Molecular Weight: 308.418
    Out of Stock Item #: H391098
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    Technical Identifiers
    IUPAC Name
    2-hydroxy-5-methoxy-3-undecylcyclohexa-2,5-diene-1,4-dione
    SMILES
    CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)OC)O
    InChIKey
    KHBJLRRAMCJZLZ-UHFFFAOYSA-N
    InChI
    1S/C18H28O4/c1-3-4-5-6-7-8-9-10-11-12-14-17(20)15(19)13-16(22-2)18(14)21/h13,20H,3-12H2,1-2H3
    Synonyms
    HY-W510159 | 4H3R9623BA | 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-5-methoxy-3-undecyl- | 2-hydroxy-5-methoxy-3-undecy...
  4. Alirocumab (anti-PCSK9)
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    Alirocumab (anti-PCSK9)
    CAS: 1245916-14-6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% 75mg/ml in buffer
    In Stock Item #: A302291
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    PCSK9
    Species reactivity（Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    C(C(COP(=O)(O)O)O)O.[Na].[Na]
    InChIKey
    CATWCRUATKKAAQ-UHFFFAOYSA-N
    InChI
    1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
    Synonyms
    BCP25199 | CID 88214187 | 1245916-14-6 | B0084-007210 | SCHEMBL7870957 | BA165582
  5. PF-06446846
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    PF-06446846
    CAS: 1632250-49-7 PubChem CID: 86271238 Formula: C22H20ClN7O Molecular Weight: 433.89
    ≥98%
    Out of Stock Item #: P412585
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    Technical Identifiers
    IUPAC Name
    N-(3-chloropyridin-2-yl)-N-[(3R)-piperidin-3-yl]-4-(triazolo[4,5-b]pyridin-3-yl)benzamide
    SMILES
    C1CC(CNC1)N(C2=C(C=CC=N2)Cl)C(=O)C3=CC=C(C=C3)N4C5=C(C=CC=N5)N=N4
    InChIKey
    FDTXHWQFIXYHCL-QGZVFWFLSA-N
    InChI
    1S/C22H20ClN7O/c23-18-5-2-12-25-20(18)29(17-4-1-11-24-14-17)22(31)15-7-9-16(10-8-15)30-21-19(27-28-30)6-3-13-26-21/h2-3,5-10,12-13,17,24H,1,4,11,14H2/show more
    Synonyms
    N-(3-Chloropyridin-2-yl)-N-((3R)-piperidin-3-yl)-4-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)benzamide
  6. R-IMPP
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    R-IMPP
    CAS: 2133832-83-2 PubChem CID: 122198706 Formula: C24H27N3O2 Molecular Weight: 389.49
    10mM in DMSO
    In Stock Item #: R422578
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-isoquinolin-1-yl-3-(4-methoxyphenyl)-N-[(3R)-piperidin-3-yl]propanamide
    SMILES
    COC1=CC=C(C=C1)CCC(=O)N(C2CCCNC2)C3=NC=CC4=CC=CC=C43
    InChIKey
    OKTGXQMSOIQCTJ-HXUWFJFHSA-N
    InChI
    1S/C24H27N3O2/c1-29-21-11-8-18(9-12-21)10-13-23(28)27(20-6-4-15-25-17-20)24-22-7-3-2-5-19(22)14-16-26-24/h2-3,5,7-9,11-12,14,16,20,25H,4,6,10,13,15,17show more
    Synonyms
    (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide | PF-00932239
  7. R-IMPP
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    R-IMPP
    CAS: 2133832-83-2 PubChem CID: 122198706 Formula: C24H27N3O2 Molecular Weight: 389.49
    ≥98%
    In Stock Item #: R414007
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-isoquinolin-1-yl-3-(4-methoxyphenyl)-N-[(3R)-piperidin-3-yl]propanamide
    SMILES
    COC1=CC=C(C=C1)CCC(=O)N(C2CCCNC2)C3=NC=CC4=CC=CC=C43
    InChIKey
    OKTGXQMSOIQCTJ-HXUWFJFHSA-N
    InChI
    1S/C24H27N3O2/c1-29-21-11-8-18(9-12-21)10-13-23(28)27(20-6-4-15-25-17-20)24-22-7-3-2-5-19(22)14-16-26-24/h2-3,5,7-9,11-12,14,16,20,25H,4,6,10,13,15,17show more
    Synonyms
    (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide | PF-00932239
  8. SBC-110736
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    SBC-110736
    CAS: 1629166-02-4 PubChem CID: 78425817 Formula: C26H27N3O2 Molecular Weight: 413.51
    10mM in DMSO
    In Stock Item #: S421998
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    Technical Identifiers
    IUPAC Name
    N-[4-[4-(4-methylphenyl)-2-phenylpiperazine-1-carbonyl]phenyl]acetamide
    SMILES
    CC1=CC=C(C=C1)N2CCN(C(C2)C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)NC(=O)C
    InChIKey
    PILMFSWQYWYOJC-UHFFFAOYSA-N
    InChI
    1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15,25H,16-18H2,1-2H3,(H,27,30)
    Synonyms
    N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide
  9. SBC-110736
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    SBC-110736
    CAS: 1629166-02-4 PubChem CID: 78425817 Formula: C26H27N3O2 Molecular Weight: 413.51
    ≥98%
    In Stock Item #: S412188
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    N-[4-[4-(4-methylphenyl)-2-phenylpiperazine-1-carbonyl]phenyl]acetamide
    SMILES
    CC1=CC=C(C=C1)N2CCN(C(C2)C3=CC=CC=C3)C(=O)C4=CC=C(C=C4)NC(=O)C
    InChIKey
    PILMFSWQYWYOJC-UHFFFAOYSA-N
    InChI
    1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15,25H,16-18H2,1-2H3,(H,27,30)
    Synonyms
    N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide
  10. SBC-115076
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    SBC-115076
    CAS: 489415-96-5 EC Number: 134-737-5 PubChem CID: 5734410 Formula: C31H33N3O5 Molecular Weight: 527.61
    10mM in DMSO
    In Stock Item #: S424240
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (4E)-4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione
    SMILES
    CC1=C(C=CC(=C1)C(=C2C(N(C(=O)C2=O)CCCN3CCOCC3)C4=CC=NC=C4)O)OCC5=CC=CC=C5
    InChIKey
    VVYIXKBHQQSREP-ORIPQNMZSA-N
    InChI
    1S/C31H33N3O5/c1-22-20-25(8-9-26(22)39-21-23-6-3-2-4-7-23)29(35)27-28(24-10-12-32-13-11-24)34(31(37)30(27)36)15-5-14-33-16-18-38-19-17-33/h2-4,6-13,20show more
    Synonyms
    4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one
  11. SBC-115076
    Wish List Compare
    SBC-115076
    CAS: 489415-96-5 PubChem CID: 5734410 Formula: C31H33N3O5 Molecular Weight: 527.61
    ≥98%
    In Stock Item #: S413896
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (4E)-4-[hydroxy-(3-methyl-4-phenylmethoxyphenyl)methylidene]-1-(3-morpholin-4-ylpropyl)-5-pyridin-4-ylpyrrolidine-2,3-dione
    SMILES
    CC1=C(C=CC(=C1)C(=C2C(N(C(=O)C2=O)CCCN3CCOCC3)C4=CC=NC=C4)O)OCC5=CC=CC=C5
    InChIKey
    VVYIXKBHQQSREP-ORIPQNMZSA-N
    InChI
    1S/C31H33N3O5/c1-22-20-25(8-9-26(22)39-21-23-6-3-2-4-7-23)29(35)27-28(24-10-12-32-13-11-24)34(31(37)30(27)36)15-5-14-33-16-18-38-19-17-33/h2-4,6-13,20show more
    Synonyms
    4-(4-(benzyloxy)-3-methylbenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one
  12. no_selection
    Wish List Compare
    Alirocumab (anti-PCSK9), Antibody of proprotein convertase subtilisin/kexin type 9
    CAS: 1245916-14-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab169266
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    PCSK9
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Species reactivity（Reacts with)
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    C(C(COP(=O)(O)O)O)O.[Na].[Na]
    InChIKey
    CATWCRUATKKAAQ-UHFFFAOYSA-N
    InChI
    1S/C3H9O6P.2Na/c4-1-3(5)2-9-10(6,7)8;;/h3-5H,1-2H2,(H2,6,7,8);;
    Synonyms
    Recombinant Alirocumab Antibody | REGN 727 | SAR 236553 | Alirocumab (anti-PCSK9) | Anti-PCSK9 Reference Antibody (al...
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