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Trk Receptor

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  1. GW441756
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    GW441756
    CAS: 504433-23-2 Formula: C17H13N3O Molecular Weight: 275.3
    ≥98%
    In Stock Item #: G129825
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    Technical Identifiers
    IUPAC Name
    (3Z)-3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one
    SMILES
    CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
    InChIKey
    NXNQLECPAXXYTR-LCYFTJDESA-N
    InChI
    1S/C17H13N3O/c1-20-10-11(12-5-2-3-7-15(12)20)9-13-16-14(19-17(13)21)6-4-8-18-16/h2-10H,1H3,(H,19,21)/b13-9-
    Synonyms
    GW441756 hydrochloride | 3-(1-Methyl-1H-indol-3-ylmethylene)-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one | BRD-K04146668-...
  2. Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
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    Lestaurtinib, Tyrosine-protein kinase receptor RET inhibitor
    CAS: 111358-88-4 Formula: C26H21N3O4 Molecular Weight: 439.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L275009
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    IUPAC Name
    (15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,1show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(CO)O
    InChIKey
    UIARLYUEJFELEN-LROUJFHJSA-N
    InChI
    1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12Hshow more
    Synonyms
    SPM-924 | (5S,6S,8R)-6-hydroxy-6-(hydroxymethyl)-5-methyl-7,8,14,15-tetrahydro-5H-16-oxa-4b,8a,14-triaza-5,8-methanod...
  3. Cyclotraxin B
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    Cyclotraxin B
    CAS: 1203586-72-4 PubChem CID: 90489002 Formula: C48H73N13O17S3 Molecular Weight: 1200.36
    ≥98%
    In Stock Item #: C288514
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    IUPAC Name
    (3S,6R,11R,17S,20S,23S,26S,32S,35S)-6-amino-20-(4-aminobutyl)-3-(2-amino-2-oxoethyl)-17-(2-carboxyethyl)-23-[(1R)-1-hydroxyethyl]-26-[(4-hydroxyphenylshow more
    SMILES
    CC(C1C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(CSSCC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)NCC(=O)NC(C(=O)N1)CC3=CC=C(C=C3)O)CCSC)CC(=O)N)N)C(=O)O)CCC(=O)O)CCCCN)O
    InChIKey
    JLBMMJHZUYBFGX-ZHTCEXBHSA-N
    InChI
    1S/C48H73N13O17S3/c1-24(62)39-46(75)58-28(6-3-4-15-49)43(72)56-29(12-13-38(67)68)41(70)52-21-37(66)55-33(48(77)78)23-81-80-22-27(50)40(69)59-32(19-35(show more
    Synonyms
    S-1203586-72-4 | Cyclotraxin B acetate | (3S,6R,11R,17S,20S,23S,26S,32S,35S)-6-amino-20-(4-aminobutyl)-3-(2-amino-2-o...
  4. N-Acetyl-5-hydroxytryptamine
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    N-Acetyl-5-hydroxytryptamine
    CAS: 1210-83-9 EC Number: 214-916-5 Formula: C12H14N2O2 Molecular Weight: 218.26
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N159247
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    IUPAC Name
    N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide
    SMILES
    CC(=O)NCCC1=CNC2=C1C=C(C=C2)O
    InChIKey
    MVAWJSIDNICKHF-UHFFFAOYSA-N
    InChI
    1S/C12H14N2O2/c1-8(15)13-5-4-9-7-14-12-3-2-10(16)6-11(9)12/h2-3,6-7,14,16H,4-5H2,1H3,(H,13,15)
    Synonyms
    Normelatonin | N-acetylserotonin | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide | 5-Hydroxy-N-acetyltryptamine
  5. Tyrphostin AG 879
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    Tyrphostin AG 879
    CAS: 148741-30-4 EC Number: 878-915-7 PubChem CID: 135419190 Formula: C18H24N2OS Molecular Weight: 316.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: T129799
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    IUPAC Name
    (E)-2-cyano-3-(3,5-ditert-butyl-4-hydroxyphenyl)prop-2-enethioamide
    SMILES
    CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C(=S)N
    InChIKey
    XRZYELWZLNAXGE-KPKJPENVSA-N
    InChI
    1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+
    Synonyms
    2-dicyclohexylphosphino-2',6' dimethoxybiphenyl | Tyrphostin AG 879 | 2-Propenethioamide, 3-(3,5-bis(1,1-dimethylethy...
  6. K-252a
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    K-252a
    CAS: 99533-80-9 EC Number: 640-127-4 Formula: C27H21N3O5 Molecular Weight: 467.47
    ≥97%(HPLC)
    Out of Stock Item #: K139531
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    Technical Identifiers
    IUPAC Name
    methyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,2show more
    SMILES
    CC12C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O
    InChIKey
    KOZFSFOOLUUIGY-SOLYNIJKSA-N
    InChI
    1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11show more
    Synonyms
    K 252 | methyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]...
  7. LarotrectinibFor, Inhibitor of neurotrophic receptor tyrosine kinase 1
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    LarotrectinibFor, Inhibitor of neurotrophic receptor tyrosine kinase 1
    CAS: 1223403-58-4 EC Number: 826-190-2 Formula: C21H22F2N6O2 Molecular Weight: 428.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: L172696
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    IUPAC Name
    (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide
    SMILES
    C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F
    InChIKey
    NYNZQNWKBKUAII-KBXCAEBGSA-N
    InChI
    1S/C21H22F2N6O2/c22-13-3-4-16(23)15(10-13)18-2-1-7-28(18)19-6-9-29-20(26-19)17(11-24-29)25-21(31)27-8-5-14(30)12-27/h3-4,6,9-11,14,18,30H,1-2,5,7-8,12show more
    Synonyms
    NYNZQNWKBKUAII-KBXCAEBGSA-N | DB14723 | Q27081513 | ARRY470 | ARRY-470 | ARRY-470; larotrectinib | AS-35231 | Larotre...
  8. 7,8-Dihydroxyflavone Hydrate
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    7,8-Dihydroxyflavone Hydrate
    CAS: 38183-03-8 EC Number: 253-812-4 Formula: C15H10O4·xH2O Molecular Weight: 254.24 (anhydrous basis)
    ≥98%(HPLC)
    In Stock Item #: D137213
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    Technical Identifiers
    IUPAC Name
    7,8-dihydroxy-2-phenylchromen-4-one
    SMILES
    C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3)O)O
    InChIKey
    COCYGNDCWFKTMF-UHFFFAOYSA-N
    InChI
    1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
    Synonyms
    NINDS_000371 | 7,8-dihydroxy-2-phenylchromen-4-one | MFCD00006836 | 7,8-Dihydroxy-2-phenyl-4-benzopyrone | 4H-1-Benzo...
  9. ANA-12
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    ANA-12
    CAS: 219766-25-3 Formula: C22H21N3O3S Molecular Weight: 407.49
    ≥96%
    In Stock Item #: A168673
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    Technical Identifiers
    IUPAC Name
    N-[2-[(2-oxoazepan-3-yl)carbamoyl]phenyl]-1-benzothiophene-2-carboxamide
    SMILES
    C1CCNC(=O)C(C1)NC(=O)C2=CC=CC=C2NC(=O)C3=CC4=CC=CC=C4S3
    InChIKey
    TUSCYCAIGRVBMD-UHFFFAOYSA-N
    InChI
    1S/C22H21N3O3S/c26-20(25-17-10-5-6-12-23-21(17)27)15-8-2-3-9-16(15)24-22(28)19-13-14-7-1-4-11-18(14)29-19/h1-4,7-9,11,13,17H,5-6,10,12H2,(H,23,27)(H,2show more
    Synonyms
    AS-16798 | DTXSID501045818 | HY-12497 | A878840 | CHEBI:140465 | ANA12 | ANA-12 | N-{2-[(2-oxoazepan-3-yl)carbamoyl]p...
  10. Amitriptyline Hydrochloride, Norepinephrine transporter inhibitor
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    Amitriptyline Hydrochloride, Norepinephrine transporter inhibitor
    CAS: 549-18-8 EC Number: 208-964-6 Formula: C20H23N · HCl Molecular Weight: 313.86
    ≥98%
    In Stock Item #: A129730
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    Technical Identifiers
    IUPAC Name
    N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride
    SMILES
    CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
    InChIKey
    KFYRPLNVJVHZGT-UHFFFAOYSA-N
    InChI
    1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
    Synonyms
    5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride | AMITRIPTYLINE HYDR...
  11. PD 90780 - ≥98%(HPLC) CAS No(77422-99-2) by Aladdin Scientific
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    PD 90780
    CAS: 77422-99-2 PubChem CID: 9885305 Formula: C19H14N4O4 Molecular Weight: 362.34
    ≥98%(HPLC)
    In Stock Item #: P287783
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    Technical Identifiers
    IUPAC Name
    7-benzamido-4-methyl-9-oxopyrazolo[5,1-b]quinazoline-2-carboxylic acid
    SMILES
    CN1C2=C(C=C(C=C2)NC(=O)C3=CC=CC=C3)C(=O)N4C1=CC(=N4)C(=O)O
    InChIKey
    IAZAGXDMMVWYKF-UHFFFAOYSA-N
    InChI
    1S/C19H14N4O4/c1-22-15-8-7-12(20-17(24)11-5-3-2-4-6-11)9-13(15)18(25)23-16(22)10-14(21-23)19(26)27/h2-10H,1H3,(H,20,24)(H,26,27)
    Synonyms
    7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid
  12. GNF 5837, Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3;Inhibitor of lanosterol synthase
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    GNF 5837, Inhibitor of neurotrophic receptor tyrosine kinase 1;Inhibitor of neurotrophic receptor tyrosine kinase 2;Inhibitor of neurotrophic receptor tyrosine kinase 3;Inhibitor of lanosterol synthase
    CAS: 1033769-28-6 EC Number: 806-102-9 Formula: C28H21F4N5O2 Molecular Weight: 535.49
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: G287150
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    Technical Identifiers
    IUPAC Name
    1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
    SMILES
    CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)C(=CC5=CC=CN5)C(=O)N4
    InChIKey
    YYDUWLSETXNJJT-MTJSOVHGSA-N
    InChI
    1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-3show more
    Synonyms
    1033769-28-6 | BDBM50384727 | YYDUWLSETXNJJT-MTJSOVHGSA-N | A896483 | Q27077827 | (Z)-1-(3-((3-((1H-pyrrol-2-yl)methy...
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