Methyl 3,5-dihydroxybenzoate - ≥98% , CAS No.2150-44-9

CAS: 2150-44-9 Cat. No.: M103567 Molecular Weight: 168.15 Beilstein Registry Number: 10405 EC Number: 218-426-2
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
AMY30290 | Z104487920 | AN-651/43112578 | cinc | EINECS 218-426-2 | Methyl 3,5-hydroxybenzoate | BDBM50428392 | Lead monosulfate | SY001681 | F3308-4032 | Zirkonium | AlCl3 | alpha-Resorcylic Acid Methyl Ester | californio | UNII-41U1BRD8AX | alpha-Resorc
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
M103567-5g
1
$9.90
10g
M103567-10g
3
$10.90
25g
M103567-25g
4

$12.90

$19.90
Save $7.00 (35.18%)
50g
M103567-50g
1

$23.90

$35.90
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100g
M103567-100g
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.

$25.90

$38.90
Save $13.00 (33.42%)
250g
M103567-250g
1

$56.90

$85.90
Save $29.00 (33.76%)
500g
M103567-500g
1

$98.90

$148.90
Save $50.00 (33.58%)
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 7 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Methyl 3,5-dihydroxybenzoate was used in the synthesis of cored dendrimers. It was also used in the preparation of bis(5-carbomethoxy-1,3-phenylene)-32-crown-10, a semi-rigid 32-membered ring diester crown ether.

The ribonucleotide reductase inhibition and antitumor activity of methyl 3, 5-dihydroxybenzoate were studied

Specifications

Synonyms
AMY30290 | Z104487920 | AN-651/43112578 | cinc | EINECS 218-426-2 | Methyl 3, 5-hydroxybenzoate | BDBM50428392 | Lead monosulfate | SY001681 | F3308-4032 | Zirkonium | AlCl3 | alpha-Resorcylic Acid Methyl Ester | californio | UNII-41U1BRD8AX | alpha-Resorc
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488185029
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488185029
Canonical SmilesCOC(=O)C1=CC(=CC(=C1)O)O
IUPAC Namemethyl 3,5-dihydroxybenzoate
InChIKeyRNVFYQUEEMZKLR-UHFFFAOYSA-N
INCHI1S/C8H8O4/c1-12-8(11)5-2-6(9)4-7(10)3-5/h2-4,9-10H,1H3
Isomeric SMILES COC(=O)C1=CC(=CC(=C1)O)O
WGK Germany 3
Molecular Weight 168.15
Beilstein 10405
Reaxy-Rn 2091651
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2091651&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Benzoic acid esters
Direct Parentm-Hydroxybenzoic acid esters
Alternative Parents Resorcinols  Benzoyl derivatives  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Methyl esters  Monocarboxylic acids and derivatives  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents M-hydroxybenzoic acid ester - Resorcinol - Benzoyl - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Methyl ester - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as m-hydroxybenzoic acid esters. These are benzoic acid esters where the benzene ring is meta-substituted with a hydroxy group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CA1 Tclin Carbonic anhydrase 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA12 Tclin Carbonic anhydrase 12 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA14 Tclin Carbonic anhydrase 14 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA9 Tclin Carbonic anhydrase 9 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA7 Tclin Carbonic anhydrase 7 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA14 Tclin Carbonic anhydrase XIV (1305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Ca7 Carbonic anhydrase VII (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ralstonia solanacearum (520 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
J774 (3120 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot NumberCertificate TypeDateItem
L2111251Certificate of AnalysisSep 17, 2025 M103567
J2109459Certificate of AnalysisJul 15, 2025 M103567
G2119043Certificate of AnalysisMay 13, 2025 M103567
G2424324Certificate of AnalysisJul 05, 2024 M103567
H2513092Certificate of AnalysisJul 05, 2024 M103567
G2424330Certificate of AnalysisJul 05, 2024 M103567
G2424329Certificate of AnalysisJul 05, 2024 M103567
G2424328Certificate of AnalysisJul 05, 2024 M103567
G2424327Certificate of AnalysisJul 05, 2024 M103567
G2424326Certificate of AnalysisJul 05, 2024 M103567
G2424325Certificate of AnalysisJul 05, 2024 M103567
G2424323Certificate of AnalysisJul 05, 2024 M103567
G2424322Certificate of AnalysisJul 05, 2024 M103567
G2424321Certificate of AnalysisJul 05, 2024 M103567
G2028137Certificate of AnalysisMay 08, 2024 M103567
G2028132Certificate of AnalysisMay 08, 2024 M103567
G2028130Certificate of AnalysisMay 08, 2024 M103567
E1927011Certificate of AnalysisMar 10, 2023 M103567
E1831175Certificate of AnalysisApr 22, 2022 M103567

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Chemical and Physical Properties
SolubilitySlightly soluble in water.
Melt Point(°C)167-170°C
Molecular Weight168.150 g/mol
XLogP31.500
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass168.042 Da
Monoisotopic Mass168.042 Da
Topological Polar Surface Area66.800 Ų
Heavy Atom Count12
Formal Charge0
Complexity158.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Jianhan Ye, Xin Lu, Xiaohuan Zhao, Fen Wu, Yuanchen Dong, Qian Shi, Lijin Xu.  (2023)  DNA-decorated multilamellar cholesterol assemblies for nucleic acid detection in the micrometer-scale solid-state nanopore.  POLYMER,      [PMID:] [10.1016/j.polymer.2023.125676]
2. Jian Yao, Lun Gui, Qizhang Long.  (2022)  A chlorogenic acid esterase from a metagenomic library with unique substrate specificity and its application in caffeic and ferulic acid production from agricultural byproducts.  BIOCATALYSIS AND BIOTRANSFORMATION,      [PMID:] [10.1080/10242422.2021.1969370]
3. Yao Jian, Gui Lun, Yin Shaocheng.  (2021)  A novel esterase from a soil metagenomic library displaying a broad substrate range.  AMB Express,  11  (1): (1-10).  [PMID:33666762] [10.1186/s13568-021-01198-5]
4. Mo Zhu, Nairong Hao, Jinxian Yang, Lianwei Li.  (2018)  A comparative study of intrachain cyclization and solution properties of long-subchain hyperbranched polymers prepared via Y-type and V-type macromonomer approaches.  Polymer Chemistry,  (20): (2830-2842).  [PMID:] [10.1039/C8PY00362A]
5. Zhukang Du, Feng Wang, Xueyi Chang, Jun Peng, Biye Ren.  (2017)  Influence of substituted structure of Percec-type mini-dendritic end groups on aggregation and rheology of hydrophobically modified ethoxylated urethanes (HEURs) in aqueous solution.  POLYMER,      [PMID:] [10.1016/j.polymer.2017.12.022]
6. Zhukang Du, Biye Ren, Xueyi Chang, Renfeng Dong, Zhen Tong.  (2017)  An End-Bifunctionalized Hydrophobically Modified Ethoxylated Urethane Model Polymer: Multiple Stimuli-Responsive Aggregation and Rheology in Aqueous Solution.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.6b02301]
7. Junli Xiao, Jianbo Jin, Shanyi Chen, Jianfeng Zhang, Peijian Cao, Li-Juan Mao, Ran Li.  (2024)  Methyl benzoate-related compounds as potential repellents and fumigants for the control of cigarette beetle, Lasioderma serricorne (F.).  JOURNAL OF STORED PRODUCTS RESEARCH,      [PMID:] [10.1016/j.jspr.2024.102276]
Solution Calculators
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