N-(2-Aminoethyl)maleimide trifluoroacetic acid salt - ≥95%(HPLC) , CAS No.146474-00-2

CAS: 146474-00-2 Cat. No.: N131107 Molecular Weight: 254.163 EC Number: 628-492-8

GRADE & PURITY ≥95%(HPLC)

Synonyms

1-(2-aminoethyl)pyrrole-2,5-dione;2,2,2-trifluoroacetic acid | N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA | 2-Maleimidoethyl amine trifluoroacetic acid | SCHEMBL247137 | N-(2-Aminoethyl)maleimide Trifluoroacetic Acid | PD131073 | N-(2-aminoethyl)maleimide t

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

227,228,229

Overview

N-(2-Aminoethyl)maleimide Trifluoroacetic Acid is a thiol-reactive cross-linking reagent.
Bifunctional Crosslinker

Specifications

Synonyms

1-(2-aminoethyl)pyrrole-2, 5-dione;2, 2, 2-trifluoroacetic acid | N-(2-AMINOETHYL)MALEIMIDE TRIFLUOROACETA | 2-Maleimidoethyl amine trifluoroacetic acid | SCHEMBL247137 | N-(2-Aminoethyl)maleimide Trifluoroacetic Acid | PD131073 | N-(2-aminoethyl)maleimide t

Specifications & Purity

≥95%(HPLC)

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥95%(HPLC)

Names and Identifiers

• Pubchem Sid: 504768191
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504768191
• Canonical Smiles: C1=CC(=O)N(C1=O)CCN.C(=O)(C(F)(F)F)O
• IUPAC Name: 1-(2-aminoethyl)pyrrole-2,5-dione;2,2,2-trifluoroacetic acid
• InChIKey: YNHKVOGCDPODMT-UHFFFAOYSA-N
• INCHI: 1S/C6H8N2O2.C2HF3O2/c7-3-4-8-5(9)1-2-6(8)10;3-2(4,5)1(6)7/h1-2H,3-4,7H2;(H,6,7)
• Isomeric SMILES: C1=CC(=O)N(C1=O)CCN.C(=O)(C(F)(F)F)O
• WGK Germany: 3
• Molecular Weight: 254.163
• Reaxy-Rn: 7558664
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7558664&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Maleimides
• Alternative Parents: N-substituted carboxylic acid imides Pyrrolines Dicarboximides Amino acids and derivatives Monocarboxylic acids and derivatives Azacyclic compounds Organopnictogen compounds Organic salts Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: Maleimide - Carboxylic acid imide, n-substituted - Carboxylic acid imide - Dicarboximide - Pyrroline - Amino acid or derivatives - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Azacycle - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxide - Amine - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organic nitrogen compound - Organic salt - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as maleimides. These are compounds containing a 2,5-pyrroledione moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (Partly), chloroform, Warm Ethanol, methanol, and DMSO.
• Sensitivity: air sensitive；heat sensitive
• Molecular Weight: 254.160 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 2
• Exact Mass: 254.051 Da
• Monoisotopic Mass: 254.051 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 263.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Xinglai Tong, Tuohao Jiang, Jiaying Yang, Ying Song, Qi Ao, Jun Tang, Ling Zhang.  (2025)  Continuous glucose monitoring (CGM) system based on protein hydrogel anti-biofouling coating for long-term accurate and point-of-care glucose monitoring.  BIOSENSORS & BIOELECTRONICS,      [PMID:40014948] [10.1016/j.bios.2025.117307]